6L5M
Crystal structure of human DEAD-box RNA helicase DDX21 in complex with AMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003724 | molecular_function | RNA helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003724 | molecular_function | RNA helicase activity |
| B | 0005524 | molecular_function | ATP binding |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0003724 | molecular_function | RNA helicase activity |
| C | 0005524 | molecular_function | ATP binding |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003724 | molecular_function | RNA helicase activity |
| D | 0005524 | molecular_function | ATP binding |
| E | 0003676 | molecular_function | nucleic acid binding |
| E | 0003724 | molecular_function | RNA helicase activity |
| E | 0005524 | molecular_function | ATP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue AMP A 601 |
| Chain | Residue |
| A | ARG204 |
| A | THR237 |
| A | HOH705 |
| B | LYS481 |
| A | GLY205 |
| A | VAL206 |
| A | PHE208 |
| A | PHE210 |
| A | GLN213 |
| A | GLY233 |
| A | GLY235 |
| A | LYS236 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue AMP B 601 |
| Chain | Residue |
| B | ARG204 |
| B | GLY205 |
| B | VAL206 |
| B | PHE208 |
| B | PHE210 |
| B | GLN213 |
| B | GLY233 |
| B | GLY235 |
| B | LYS236 |
| B | THR237 |
| B | GLN275 |
| B | HOH707 |
| C | LYS481 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue AMP C 601 |
| Chain | Residue |
| C | ARG204 |
| C | GLY205 |
| C | VAL206 |
| C | PHE208 |
| C | PHE210 |
| C | GLN213 |
| C | GLY233 |
| C | GLY235 |
| C | LYS236 |
| C | THR237 |
| C | HOH705 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue AMP D 601 |
| Chain | Residue |
| D | ARG204 |
| D | GLY205 |
| D | VAL206 |
| D | PHE208 |
| D | PHE210 |
| D | GLN213 |
| D | GLY233 |
| D | GLY235 |
| D | LYS236 |
| D | THR237 |
| E | ILE478 |
| E | LYS481 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue AMP E 601 |
| Chain | Residue |
| E | ARG204 |
| E | GLY205 |
| E | VAL206 |
| E | PHE208 |
| E | PHE210 |
| E | GLN213 |
| E | GLY233 |
| E | GLY235 |
| E | LYS236 |
| E | THR237 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 895 |
| Details | Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 15 |
| Details | Motif: {"description":"DEAD box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 35 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
