6L4G
Crystal structure of human NDRG3 I171M/S176H mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003674 | molecular_function | molecular_function |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0007165 | biological_process | signal transduction |
| A | 0007283 | biological_process | spermatogenesis |
| A | 0030154 | biological_process | cell differentiation |
| A | 0030308 | biological_process | negative regulation of cell growth |
| A | 0070062 | cellular_component | extracellular exosome |
| B | 0003674 | molecular_function | molecular_function |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0007165 | biological_process | signal transduction |
| B | 0007283 | biological_process | spermatogenesis |
| B | 0030154 | biological_process | cell differentiation |
| B | 0030308 | biological_process | negative regulation of cell growth |
| B | 0070062 | cellular_component | extracellular exosome |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| A | MET1 | |
| B | MET1 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648 |
| Chain | Residue | Details |
| A | THR322 | |
| B | THR322 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | THR329 | |
| A | THR332 | |
| A | THR355 | |
| B | THR329 | |
| B | THR332 | |
| B | THR355 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER331 | |
| B | SER331 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER334 | |
| A | SER338 | |
| A | SER341 | |
| B | SER334 | |
| B | SER338 | |
| B | SER341 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER335 | |
| B | SER335 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648 |
| Chain | Residue | Details |
| A | SER352 | |
| A | SER374 | |
| B | SER352 | |
| B | SER374 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9QYF9 |
| Chain | Residue | Details |
| A | SER361 | |
| B | SER361 |
