6L42

Structure of severe fever with thrombocytopenia syndrome virus L protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001172	biological_process	RNA-templated transcription
A	0003968	molecular_function	RNA-dependent RNA polymerase activity
A	0006351	biological_process	DNA-templated transcription
A	0016740	molecular_function	transferase activity
A	0016787	molecular_function	hydrolase activity
A	0019079	biological_process	viral genome replication
A	0044165	cellular_component	host cell endoplasmic reticulum
A	0044172	cellular_component	host cell endoplasmic reticulum-Golgi intermediate compartment
A	0044177	cellular_component	host cell Golgi apparatus
A	0044423	cellular_component	virion component
A	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: For endonuclease activity => ECO:0000303|PubMed:31914382

Chain	Residue	Details
A	LYS145

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250|UniProtKB:A5HC98

Chain	Residue	Details
A	HIS80
A	ASP112
A	GLU126

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:32313945, ECO:0000269|PubMed:32341479

Chain	Residue	Details
A	ASP1127

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site_id	SWS_FT_FI4
Number of Residues	4
Details	SITE: Interaction with the cap substrate => ECO:0000250|UniProtKB:A2SZS3

Chain	Residue	Details
A	PHE1703
A	GLN1707
A	TYR1719
A	LEU1772

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