6L3A
Cytochrome P450 107G1 (RapN) with everolimus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0020037 | molecular_function | heme binding |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue HEM A 501 |
| Chain | Residue |
| A | PHE62 |
| A | THR245 |
| A | THR246 |
| A | ARG295 |
| A | SER345 |
| A | HIS351 |
| A | CYS353 |
| A | MET354 |
| A | GLY355 |
| A | LEU358 |
| A | VAL359 |
| A | ARG69 |
| A | ILE90 |
| A | MET91 |
| A | HIS98 |
| A | ARG102 |
| A | LEU238 |
| A | ALA241 |
| A | GLY242 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue E53 B 502 |
| Chain | Residue |
| B | ALA83 |
| B | GLN85 |
| B | GLN87 |
| B | MET91 |
| B | LEU176 |
| B | VAL186 |
| B | MET187 |
| B | ALA241 |
| B | THR245 |
| B | ILE287 |
| B | TRP293 |
| B | HEM501 |
| B | HOH603 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide HEC B 501 and HIS B 351 |
| Chain | Residue |
| B | PHE62 |
| B | ARG69 |
| B | ILE90 |
| B | MET93 |
| B | HIS98 |
| B | ARG102 |
| B | LEU238 |
| B | ALA241 |
| B | GLY242 |
| B | THR245 |
| B | ARG295 |
| B | SER345 |
| B | LEU346 |
| B | GLY347 |
| B | GLY349 |
| B | ALA350 |
| B | HIS352 |
| B | CYS353 |
| B | MET354 |
| B | GLY355 |
| B | LEU358 |
| B | VAL359 |
| B | E53502 |
