6L2Z
IlvC, a ketol-acid reductoisomerase, from Streptococcus pnuemoniae_D191G
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| A | 0009097 | biological_process | isoleucine biosynthetic process |
| A | 0009099 | biological_process | valine biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050661 | molecular_function | NADP binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| B | 0009097 | biological_process | isoleucine biosynthetic process |
| B | 0009099 | biological_process | valine biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 35 |
| Details | binding site for residue NAP A 401 |
| Chain | Residue |
| A | TYR26 |
| A | PRO82 |
| A | ASP83 |
| A | ILE85 |
| A | GLN86 |
| A | LEU89 |
| A | ALA107 |
| A | HIS108 |
| A | HOH508 |
| A | HOH525 |
| A | HOH533 |
| A | GLY27 |
| A | HOH550 |
| A | HOH558 |
| A | HOH572 |
| A | HOH587 |
| A | HOH618 |
| A | HOH622 |
| A | HOH627 |
| A | HOH638 |
| A | HOH643 |
| A | HOH644 |
| A | SER28 |
| A | HOH652 |
| A | HOH698 |
| B | SER250 |
| B | ILE251 |
| B | SER252 |
| B | HOH559 |
| A | GLN29 |
| A | VAL48 |
| A | ARG49 |
| A | SER53 |
| A | LEU80 |
| A | ALA81 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | ALA255 |
| A | HOH580 |
| A | HOH678 |
| A | HOH699 |
| B | GLU195 |
| B | NAP401 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | ARG306 |
| A | HOH504 |
| A | HOH537 |
| B | ASN253 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | SER252 |
| A | ASN253 |
| A | THR254 |
| A | HOH503 |
| A | HOH668 |
| B | PRO82 |
| B | ASP83 |
| B | GLU84 |
| site_id | AC5 |
| Number of Residues | 30 |
| Details | binding site for residue NAP B 401 |
| Chain | Residue |
| A | SER250 |
| A | SER252 |
| A | SO4402 |
| A | HOH503 |
| A | HOH580 |
| A | HOH591 |
| B | TYR26 |
| B | GLY27 |
| B | SER28 |
| B | GLN29 |
| B | VAL48 |
| B | ARG49 |
| B | SER53 |
| B | LEU80 |
| B | ALA81 |
| B | PRO82 |
| B | ASP83 |
| B | ILE85 |
| B | GLN86 |
| B | ALA107 |
| B | HIS108 |
| B | NH4403 |
| B | HOH505 |
| B | HOH529 |
| B | HOH538 |
| B | HOH553 |
| B | HOH599 |
| B | HOH623 |
| B | HOH647 |
| B | HOH661 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| A | ASN253 |
| B | ARG299 |
| B | ARG306 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue NH4 B 403 |
| Chain | Residue |
| B | ASP83 |
| B | HIS108 |
| B | NAP401 |
| B | HOH581 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00435 |
| Chain | Residue | Details |
| A | HIS108 | |
| B | HIS108 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00435 |
| Chain | Residue | Details |
| A | TYR26 | |
| A | SER252 | |
| B | TYR26 | |
| B | ARG49 | |
| B | SER53 | |
| B | ASP83 | |
| B | GLY134 | |
| B | GLY191 | |
| B | GLU195 | |
| B | GLU227 | |
| B | GLU231 | |
| A | ARG49 | |
| B | SER252 | |
| A | SER53 | |
| A | ASP83 | |
| A | GLY134 | |
| A | GLY191 | |
| A | GLU195 | |
| A | GLU227 | |
| A | GLU231 |
