6L2K
IlvC, a ketol-acid reductoisomerase, from Streptococcus pneumoniae_R49E
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| A | 0009097 | biological_process | isoleucine biosynthetic process |
| A | 0009099 | biological_process | valine biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050661 | molecular_function | NADP binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| B | 0009097 | biological_process | isoleucine biosynthetic process |
| B | 0009099 | biological_process | valine biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 401 |
| Chain | Residue |
| A | ARG299 |
| A | ARG306 |
| B | ASN253 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| B | PRO82 |
| B | ASP83 |
| B | GLU84 |
| A | SER252 |
| A | ASN253 |
| A | THR254 |
| A | HOH502 |
| A | HOH510 |
| A | HOH524 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 401 |
| Chain | Residue |
| A | ASN253 |
| B | ARG299 |
| B | ARG306 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| B | GLY27 |
| B | SER28 |
| B | GLN29 |
| B | HOH556 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00435 |
| Chain | Residue | Details |
| A | HIS108 | |
| B | HIS108 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00435 |
| Chain | Residue | Details |
| A | TYR26 | |
| A | SER252 | |
| B | TYR26 | |
| B | GLU49 | |
| B | SER53 | |
| B | ASP83 | |
| B | GLY134 | |
| B | ASP191 | |
| B | GLU195 | |
| B | GLU227 | |
| B | GLU231 | |
| A | GLU49 | |
| B | SER252 | |
| A | SER53 | |
| A | ASP83 | |
| A | GLY134 | |
| A | ASP191 | |
| A | GLU195 | |
| A | GLU227 | |
| A | GLU231 |
