6L0T

Crystal structure of senecavirus A 3C protease

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004197	molecular_function	cysteine-type endopeptidase activity
A	0006508	biological_process	proteolysis
B	0004197	molecular_function	cysteine-type endopeptidase activity
B	0006508	biological_process	proteolysis

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: For protease 3C activity and deubiquitinase activity => ECO:0000255|PROSITE-ProRule:PRU01222, ECO:0000269|PubMed:30408499

Chain	Residue	Details
A	HIS48
A	CYS160
B	HIS48
B	CYS160

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: For protease 3C activity => ECO:0000255|PROSITE-ProRule:PRU01222

Chain	Residue	Details
A	ASP84
B	ASP84

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site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Cleavage; by protease 3C => ECO:0000269|PubMed:35727031, ECO:0000305|PubMed:18420805

Chain	Residue	Details
A	GLN211
B	GLN211

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