6KY5

Crystal structure of a hydrolase mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016787	molecular_function	hydrolase activity
B	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue SO4 A 301

Chain	Residue
A	SER121
A	ARG168
A	ASN172
A	HOH504

---

site_id	AC2
Number of Residues	8
Details	binding site for residue SO4 A 302

Chain	Residue
A	HOH518
A	HOH548
A	HOH558
A	ALA89
A	ARG90
A	SER92
A	SER93
A	HOH436

---

site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 A 303

Chain	Residue
A	ARG285
A	HOH404
B	ARG285
B	THR286
B	HOH433

---

site_id	AC4
Number of Residues	8
Details	binding site for residue SO4 A 304

Chain	Residue
A	ASN173
A	PRO174
A	SER175
A	HOH521
B	ARG90
B	SER115
B	THR116
B	HOH501

---

site_id	AC5
Number of Residues	3
Details	binding site for residue SO4 A 305

Chain	Residue
A	TYR32
A	LYS177
A	ASN264

---

site_id	AC6
Number of Residues	2
Details	binding site for residue SO4 A 306

Chain	Residue
A	ASN288
A	HOH423

---

site_id	AC7
Number of Residues	5
Details	binding site for residue SO4 A 307

Chain	Residue
A	TYR119
A	SER121
A	SER122
A	HOH407
A	HOH465

---

site_id	AC8
Number of Residues	1
Details	binding site for residue SO4 A 308

Chain	Residue
A	ARG168

---

site_id	AC9
Number of Residues	8
Details	binding site for residue SO4 B 301

Chain	Residue
A	GLY86
A	TYR87
A	SER160
A	MET161
A	HIS237
B	ARG132
B	HOH423
B	HOH508

---

site_id	AD1
Number of Residues	7
Details	binding site for residue SO4 B 302

Chain	Residue
A	ARG285
A	HOH422
B	ASP283
B	ARG285
B	HOH526
B	HOH531
B	HOH538

---

site_id	AD2
Number of Residues	5
Details	binding site for residue SO4 B 303

Chain	Residue
B	TYR32
B	ARG153
B	LYS177
B	ASN264
B	HOH430

---

site_id	AD3
Number of Residues	6
Details	binding site for residue SO4 B 304

Chain	Residue
B	SER121
B	ARG168
B	ASN172
B	HOH401
B	HOH404
B	HOH405

---

site_id	AD4
Number of Residues	5
Details	binding site for residue SO4 B 305

Chain	Residue
B	THR286
B	ALA287
B	ASN288
B	HOH520
B	HOH574

---

site_id	AD5
Number of Residues	2
Details	binding site for residue SO4 B 306

Chain	Residue
B	ARG53
B	SER54

---

site_id	AD6
Number of Residues	3
Details	binding site for residue SO4 B 307

Chain	Residue
B	PHE55
B	THR56
B	HOH415

---

site_id	AD7
Number of Residues	2
Details	binding site for residue SO4 B 308

Chain	Residue
A	ASN212
B	ARG224

---

site_id	AD8
Number of Residues	10
Details	binding site for residue SO4 B 309

Chain	Residue
A	SER61
B	ASN205
B	ASP206
B	SER207
B	ILE208
B	SER236
B	HIS237
B	HOH525
B	HOH552
B	HOH594

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"29235460","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"29374183","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"29603535","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"29666242","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"29235460","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"29374183","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"29603535","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"29666242","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29235460","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29235460","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"29666242","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---