6KW3

The ClassA RSC-Nucleosome Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000785	cellular_component	chromatin
A	0003674	molecular_function	molecular_function
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0006325	biological_process	chromatin organization
A	0006337	biological_process	nucleosome disassembly
A	0006338	biological_process	chromatin remodeling
A	0006351	biological_process	DNA-templated transcription
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0006368	biological_process	transcription elongation by RNA polymerase II
A	0016586	cellular_component	RSC-type complex
A	0042802	molecular_function	identical protein binding
B	0000786	cellular_component	nucleosome
B	0003677	molecular_function	DNA binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005694	cellular_component	chromosome
B	0006334	biological_process	nucleosome assembly
B	0030527	molecular_function	structural constituent of chromatin
B	0031507	biological_process	heterochromatin formation
B	0046982	molecular_function	protein heterodimerization activity
C	0000785	cellular_component	chromatin
C	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
C	0003677	molecular_function	DNA binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0006303	biological_process	double-strand break repair via nonhomologous end joining
C	0006325	biological_process	chromatin organization
C	0006337	biological_process	nucleosome disassembly
C	0006338	biological_process	chromatin remodeling
C	0006351	biological_process	DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription
C	0006368	biological_process	transcription elongation by RNA polymerase II
C	0008270	molecular_function	zinc ion binding
C	0016586	cellular_component	RSC-type complex
C	0043565	molecular_function	sequence-specific DNA binding
C	0045944	biological_process	positive regulation of transcription by RNA polymerase II
C	0046872	molecular_function	metal ion binding
D	0000785	cellular_component	chromatin
D	0003677	molecular_function	DNA binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0006303	biological_process	double-strand break repair via nonhomologous end joining
D	0006325	biological_process	chromatin organization
D	0006337	biological_process	nucleosome disassembly
D	0006338	biological_process	chromatin remodeling
D	0006351	biological_process	DNA-templated transcription
D	0006355	biological_process	regulation of DNA-templated transcription
D	0006368	biological_process	transcription elongation by RNA polymerase II
D	0008270	molecular_function	zinc ion binding
D	0016514	cellular_component	SWI/SNF complex
D	0016586	cellular_component	RSC-type complex
D	0042393	molecular_function	histone binding
D	0042802	molecular_function	identical protein binding
D	0045893	biological_process	positive regulation of DNA-templated transcription
D	0046872	molecular_function	metal ion binding
E	0000086	biological_process	G2/M transition of mitotic cell cycle
E	0000785	cellular_component	chromatin
E	0003682	molecular_function	chromatin binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0006337	biological_process	nucleosome disassembly
E	0006338	biological_process	chromatin remodeling
E	0006351	biological_process	DNA-templated transcription
E	0006368	biological_process	transcription elongation by RNA polymerase II
E	0016586	cellular_component	RSC-type complex
f	0000785	cellular_component	chromatin
f	0003674	molecular_function	molecular_function
f	0003682	molecular_function	chromatin binding
f	0005198	molecular_function	structural molecule activity
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0006325	biological_process	chromatin organization
f	0006337	biological_process	nucleosome disassembly
f	0006338	biological_process	chromatin remodeling
f	0006351	biological_process	DNA-templated transcription
f	0006355	biological_process	regulation of DNA-templated transcription
f	0006357	biological_process	regulation of transcription by RNA polymerase II
f	0006368	biological_process	transcription elongation by RNA polymerase II
f	0016514	cellular_component	SWI/SNF complex
f	0016586	cellular_component	RSC-type complex
f	0035267	cellular_component	NuA4 histone acetyltransferase complex
f	0045944	biological_process	positive regulation of transcription by RNA polymerase II
F	0000785	cellular_component	chromatin
F	0003674	molecular_function	molecular_function
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0006325	biological_process	chromatin organization
F	0006337	biological_process	nucleosome disassembly
F	0006338	biological_process	chromatin remodeling
F	0006351	biological_process	DNA-templated transcription
F	0006368	biological_process	transcription elongation by RNA polymerase II
F	0016586	cellular_component	RSC-type complex
F	0031490	molecular_function	chromatin DNA binding
F	0042802	molecular_function	identical protein binding
g	0000785	cellular_component	chromatin
g	0005198	molecular_function	structural molecule activity
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0006325	biological_process	chromatin organization
g	0006337	biological_process	nucleosome disassembly
g	0006338	biological_process	chromatin remodeling
g	0006351	biological_process	DNA-templated transcription
g	0006355	biological_process	regulation of DNA-templated transcription
g	0006357	biological_process	regulation of transcription by RNA polymerase II
g	0006368	biological_process	transcription elongation by RNA polymerase II
g	0016514	cellular_component	SWI/SNF complex
g	0016586	cellular_component	RSC-type complex
g	0045944	biological_process	positive regulation of transcription by RNA polymerase II
G	0000086	biological_process	G2/M transition of mitotic cell cycle
G	0000228	cellular_component	nuclear chromosome
G	0000785	cellular_component	chromatin
G	0003712	molecular_function	transcription coregulator activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0006302	biological_process	double-strand break repair
G	0006325	biological_process	chromatin organization
G	0006337	biological_process	nucleosome disassembly
G	0006338	biological_process	chromatin remodeling
G	0006351	biological_process	DNA-templated transcription
G	0006357	biological_process	regulation of transcription by RNA polymerase II
G	0006368	biological_process	transcription elongation by RNA polymerase II
G	0007059	biological_process	chromosome segregation
G	0016586	cellular_component	RSC-type complex
G	0031491	molecular_function	nucleosome binding
G	0033262	biological_process	regulation of nuclear cell cycle DNA replication
G	0034080	biological_process	CENP-A containing chromatin assembly
h	0000785	cellular_component	chromatin
h	0005515	molecular_function	protein binding
h	0005634	cellular_component	nucleus
h	0006337	biological_process	nucleosome disassembly
h	0006338	biological_process	chromatin remodeling
h	0006351	biological_process	DNA-templated transcription
h	0006357	biological_process	regulation of transcription by RNA polymerase II
h	0006368	biological_process	transcription elongation by RNA polymerase II
h	0007059	biological_process	chromosome segregation
h	0015616	molecular_function	DNA translocase activity
h	0016514	cellular_component	SWI/SNF complex
h	0016586	cellular_component	RSC-type complex
H	0000785	cellular_component	chromatin
H	0003677	molecular_function	DNA binding
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0006303	biological_process	double-strand break repair via nonhomologous end joining
H	0006325	biological_process	chromatin organization
H	0006337	biological_process	nucleosome disassembly
H	0006338	biological_process	chromatin remodeling
H	0006351	biological_process	DNA-templated transcription
H	0006355	biological_process	regulation of DNA-templated transcription
H	0006368	biological_process	transcription elongation by RNA polymerase II
H	0008270	molecular_function	zinc ion binding
H	0016514	cellular_component	SWI/SNF complex
H	0016586	cellular_component	RSC-type complex
H	0042393	molecular_function	histone binding
H	0042802	molecular_function	identical protein binding
H	0045893	biological_process	positive regulation of DNA-templated transcription
H	0046872	molecular_function	metal ion binding
I	0000785	cellular_component	chromatin
I	0005198	molecular_function	structural molecule activity
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0006325	biological_process	chromatin organization
I	0006337	biological_process	nucleosome disassembly
I	0006338	biological_process	chromatin remodeling
I	0006351	biological_process	DNA-templated transcription
I	0016586	cellular_component	RSC-type complex
I	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
J	0000166	molecular_function	nucleotide binding
J	0000775	cellular_component	chromosome, centromeric region
J	0000785	cellular_component	chromatin
J	0003677	molecular_function	DNA binding
J	0003678	molecular_function	DNA helicase activity
J	0003682	molecular_function	chromatin binding
J	0003824	molecular_function	catalytic activity
J	0004386	molecular_function	helicase activity
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005634	cellular_component	nucleus
J	0006284	biological_process	base-excision repair
J	0006302	biological_process	double-strand break repair
J	0006325	biological_process	chromatin organization
J	0006337	biological_process	nucleosome disassembly
J	0006338	biological_process	chromatin remodeling
J	0006351	biological_process	DNA-templated transcription
J	0006355	biological_process	regulation of DNA-templated transcription
J	0006366	biological_process	transcription by RNA polymerase II
J	0006368	biological_process	transcription elongation by RNA polymerase II
J	0007010	biological_process	cytoskeleton organization
J	0007059	biological_process	chromosome segregation
J	0010468	biological_process	regulation of gene expression
J	0015616	molecular_function	DNA translocase activity
J	0016586	cellular_component	RSC-type complex
J	0016787	molecular_function	hydrolase activity
J	0016887	molecular_function	ATP hydrolysis activity
J	0031507	biological_process	heterochromatin formation
J	0034080	biological_process	CENP-A containing chromatin assembly
J	0042393	molecular_function	histone binding
J	0045944	biological_process	positive regulation of transcription by RNA polymerase II
J	0051321	biological_process	meiotic cell cycle
J	0140008	molecular_function	histone H4 reader activity
J	0140015	molecular_function	histone H3K14ac reader activity
J	0140054	molecular_function	histone H2A reader activity
J	0140658	molecular_function	ATP-dependent chromatin remodeler activity
J	0140750	molecular_function	nucleosome array spacer activity
K	0000785	cellular_component	chromatin
K	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
K	0003677	molecular_function	DNA binding
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0006325	biological_process	chromatin organization
K	0006337	biological_process	nucleosome disassembly
K	0006338	biological_process	chromatin remodeling
K	0006351	biological_process	DNA-templated transcription
K	0006355	biological_process	regulation of DNA-templated transcription
K	0006368	biological_process	transcription elongation by RNA polymerase II
K	0008270	molecular_function	zinc ion binding
K	0016586	cellular_component	RSC-type complex
K	0033262	biological_process	regulation of nuclear cell cycle DNA replication
K	0042802	molecular_function	identical protein binding
K	0043565	molecular_function	sequence-specific DNA binding
K	0045944	biological_process	positive regulation of transcription by RNA polymerase II
K	0046872	molecular_function	metal ion binding
L	0000724	biological_process	double-strand break repair via homologous recombination
L	0003682	molecular_function	chromatin binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0006276	biological_process	plasmid maintenance
L	0006303	biological_process	double-strand break repair via nonhomologous end joining
L	0006325	biological_process	chromatin organization
L	0006337	biological_process	nucleosome disassembly
L	0006338	biological_process	chromatin remodeling
L	0006351	biological_process	DNA-templated transcription
L	0006368	biological_process	transcription elongation by RNA polymerase II
L	0007059	biological_process	chromosome segregation
L	0007062	biological_process	sister chromatid cohesion
L	0016586	cellular_component	RSC-type complex
L	0030435	biological_process	sporulation resulting in formation of a cellular spore
L	0042173	biological_process	regulation of sporulation resulting in formation of a cellular spore
L	0070914	biological_process	UV-damage excision repair
M	0000785	cellular_component	chromatin
M	0003677	molecular_function	DNA binding
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0006325	biological_process	chromatin organization
M	0006337	biological_process	nucleosome disassembly
M	0006338	biological_process	chromatin remodeling
M	0006351	biological_process	DNA-templated transcription
M	0006355	biological_process	regulation of DNA-templated transcription
M	0006357	biological_process	regulation of transcription by RNA polymerase II
M	0006368	biological_process	transcription elongation by RNA polymerase II
M	0009303	biological_process	rRNA transcription
M	0016586	cellular_component	RSC-type complex
N	0000786	cellular_component	nucleosome
N	0003677	molecular_function	DNA binding
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005694	cellular_component	chromosome
N	0030527	molecular_function	structural constituent of chromatin
N	0031492	molecular_function	nucleosomal DNA binding
N	0031507	biological_process	heterochromatin formation
N	0046982	molecular_function	protein heterodimerization activity
O	0000786	cellular_component	nucleosome
O	0003677	molecular_function	DNA binding
O	0005634	cellular_component	nucleus
O	0005694	cellular_component	chromosome
O	0030527	molecular_function	structural constituent of chromatin
O	0031507	biological_process	heterochromatin formation
O	0046982	molecular_function	protein heterodimerization activity
P	0000786	cellular_component	nucleosome
P	0002227	biological_process	innate immune response in mucosa
P	0003677	molecular_function	DNA binding
P	0005515	molecular_function	protein binding
P	0005615	cellular_component	extracellular space
P	0005634	cellular_component	nucleus
P	0005694	cellular_component	chromosome
P	0006325	biological_process	chromatin organization
P	0019731	biological_process	antibacterial humoral response
P	0030527	molecular_function	structural constituent of chromatin
P	0031507	biological_process	heterochromatin formation
P	0046982	molecular_function	protein heterodimerization activity
P	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
Q	0000786	cellular_component	nucleosome
Q	0003677	molecular_function	DNA binding
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005694	cellular_component	chromosome
Q	0030527	molecular_function	structural constituent of chromatin
Q	0031492	molecular_function	nucleosomal DNA binding
Q	0031507	biological_process	heterochromatin formation
Q	0046982	molecular_function	protein heterodimerization activity
R	0000786	cellular_component	nucleosome
R	0003677	molecular_function	DNA binding
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005694	cellular_component	chromosome
R	0006334	biological_process	nucleosome assembly
R	0030527	molecular_function	structural constituent of chromatin
R	0031507	biological_process	heterochromatin formation
R	0046982	molecular_function	protein heterodimerization activity
S	0000786	cellular_component	nucleosome
S	0003677	molecular_function	DNA binding
S	0005634	cellular_component	nucleus
S	0005694	cellular_component	chromosome
S	0030527	molecular_function	structural constituent of chromatin
S	0031507	biological_process	heterochromatin formation
S	0046982	molecular_function	protein heterodimerization activity
T	0000786	cellular_component	nucleosome
T	0002227	biological_process	innate immune response in mucosa
T	0003677	molecular_function	DNA binding
T	0005515	molecular_function	protein binding
T	0005615	cellular_component	extracellular space
T	0005634	cellular_component	nucleus
T	0005694	cellular_component	chromosome
T	0006325	biological_process	chromatin organization
T	0019731	biological_process	antibacterial humoral response
T	0030527	molecular_function	structural constituent of chromatin
T	0031507	biological_process	heterochromatin formation
T	0046982	molecular_function	protein heterodimerization activity
T	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
W	0000166	molecular_function	nucleotide binding
W	0000775	cellular_component	chromosome, centromeric region
W	0000785	cellular_component	chromatin
W	0003677	molecular_function	DNA binding
W	0003678	molecular_function	DNA helicase activity
W	0003682	molecular_function	chromatin binding
W	0003824	molecular_function	catalytic activity
W	0004386	molecular_function	helicase activity
W	0005515	molecular_function	protein binding
W	0005524	molecular_function	ATP binding
W	0005634	cellular_component	nucleus
W	0006284	biological_process	base-excision repair
W	0006302	biological_process	double-strand break repair
W	0006325	biological_process	chromatin organization
W	0006337	biological_process	nucleosome disassembly
W	0006338	biological_process	chromatin remodeling
W	0006351	biological_process	DNA-templated transcription
W	0006355	biological_process	regulation of DNA-templated transcription
W	0006366	biological_process	transcription by RNA polymerase II
W	0006368	biological_process	transcription elongation by RNA polymerase II
W	0007010	biological_process	cytoskeleton organization
W	0007059	biological_process	chromosome segregation
W	0010468	biological_process	regulation of gene expression
W	0015616	molecular_function	DNA translocase activity
W	0016586	cellular_component	RSC-type complex
W	0016787	molecular_function	hydrolase activity
W	0016887	molecular_function	ATP hydrolysis activity
W	0031507	biological_process	heterochromatin formation
W	0034080	biological_process	CENP-A containing chromatin assembly
W	0042393	molecular_function	histone binding
W	0045944	biological_process	positive regulation of transcription by RNA polymerase II
W	0051321	biological_process	meiotic cell cycle
W	0140008	molecular_function	histone H4 reader activity
W	0140015	molecular_function	histone H3K14ac reader activity
W	0140054	molecular_function	histone H2A reader activity
W	0140658	molecular_function	ATP-dependent chromatin remodeler activity
W	0140750	molecular_function	nucleosome array spacer activity
X	0000785	cellular_component	chromatin
X	0003682	molecular_function	chromatin binding
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0006325	biological_process	chromatin organization
X	0006337	biological_process	nucleosome disassembly
X	0006338	biological_process	chromatin remodeling
X	0006351	biological_process	DNA-templated transcription
X	0006366	biological_process	transcription by RNA polymerase II
X	0006368	biological_process	transcription elongation by RNA polymerase II
X	0016586	cellular_component	RSC-type complex
X	0042802	molecular_function	identical protein binding
X	0140006	molecular_function	histone H3 reader activity
X	0140008	molecular_function	histone H4 reader activity
Y	0000166	molecular_function	nucleotide binding
Y	0000775	cellular_component	chromosome, centromeric region
Y	0000785	cellular_component	chromatin
Y	0003677	molecular_function	DNA binding
Y	0003678	molecular_function	DNA helicase activity
Y	0003682	molecular_function	chromatin binding
Y	0003824	molecular_function	catalytic activity
Y	0004386	molecular_function	helicase activity
Y	0005515	molecular_function	protein binding
Y	0005524	molecular_function	ATP binding
Y	0005634	cellular_component	nucleus
Y	0006284	biological_process	base-excision repair
Y	0006302	biological_process	double-strand break repair
Y	0006325	biological_process	chromatin organization
Y	0006337	biological_process	nucleosome disassembly
Y	0006338	biological_process	chromatin remodeling
Y	0006351	biological_process	DNA-templated transcription
Y	0006355	biological_process	regulation of DNA-templated transcription
Y	0006366	biological_process	transcription by RNA polymerase II
Y	0006368	biological_process	transcription elongation by RNA polymerase II
Y	0007010	biological_process	cytoskeleton organization
Y	0007059	biological_process	chromosome segregation
Y	0010468	biological_process	regulation of gene expression
Y	0015616	molecular_function	DNA translocase activity
Y	0016586	cellular_component	RSC-type complex
Y	0016787	molecular_function	hydrolase activity
Y	0016887	molecular_function	ATP hydrolysis activity
Y	0031507	biological_process	heterochromatin formation
Y	0034080	biological_process	CENP-A containing chromatin assembly
Y	0042393	molecular_function	histone binding
Y	0045944	biological_process	positive regulation of transcription by RNA polymerase II
Y	0051321	biological_process	meiotic cell cycle
Y	0140008	molecular_function	histone H4 reader activity
Y	0140015	molecular_function	histone H3K14ac reader activity
Y	0140054	molecular_function	histone H2A reader activity
Y	0140658	molecular_function	ATP-dependent chromatin remodeler activity
Y	0140750	molecular_function	nucleosome array spacer activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN H 1001

Chain	Residue
H	CYS260
H	CYS263
H	CYS283
H	CYS286

---

Functional Information from PROSITE/UniProt

site_id	PS00046
Number of Residues	7
Details	HISTONE_H2A Histone H2A signature. AGLqFPV

Chain	Residue	Details
O	ALA21-VAL27

---

site_id	PS00047
Number of Residues	5
Details	HISTONE_H4 Histone H4 signature. GAKRH

Chain	Residue	Details
B	GLY14-HIS18

---

site_id	PS00322
Number of Residues	7
Details	HISTONE_H3_1 Histone H3 signature 1. KAPRKQL

Chain	Residue	Details
N	LYS14-LEU20

---

site_id	PS00357
Number of Residues	23
Details	HISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG

Chain	Residue	Details
T	ARG92-GLY114

---

site_id	PS00463
Number of Residues	30
Details	ZN2_CY6_FUNGAL_1 Zn(2)-C6 fungal-type DNA-binding domain signature. ACvqCRkrKigCdrvkpi......CgnCmkhnkmd.C

Chain	Residue	Details
K	ALA13-CYS42
C	ALA14-CYS43

---

site_id	PS00633
Number of Residues	56
Details	BROMODOMAIN_1 Bromodomain signature. SpiFnvlpPkkdyp..DYYavIknpVsfntLkkriph....Ytdaqqfmndvvq.IpwNAktY

Chain	Residue	Details
L	SER40-TYR95
X	PHE77-TYR133
X	SER210-PHE267
Y	THR1275-TYR1332

---

site_id	PS00959
Number of Residues	9
Details	HISTONE_H3_2 Histone H3 signature 2. PFqRLVREI

Chain	Residue	Details
N	PRO66-ILE74

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	Modified residue: {"description":"N6-propionyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by PAK2","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"N6-glutaryllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1); alternate","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	4
Details	DNA binding: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"UniProtKB","id":"P68431","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P84228","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	2
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P84243","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	2
Details	Modified residue: {"description":"N6-glutaryllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	2
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	2
Details	Modified residue: {"description":"N6-(2-hydroxyisobutyryl)lysine; alternate","evidences":[{"source":"UniProtKB","id":"P0C0S8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	4
Details	Modified residue: {"description":"N6-(2-hydroxyisobutyryl)lysine","evidences":[{"source":"UniProtKB","id":"P0C0S8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P0C0S8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	2
Details	Modified residue: {"description":"N5-methylglutamine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	2
Details	Modified residue: {"description":"N6-glutaryllysine; alternate","evidences":[{"source":"UniProtKB","id":"P0C0S8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	6
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	161
Details	Domain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	3
Details	Motif: {"description":"DEGH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	7
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	194
Details	Domain: {"description":"SWIRM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00247","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	52
Details	Domain: {"description":"SANT","evidences":[{"source":"PROSITE-ProRule","id":"PRU00624","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	54
Details	Zinc finger: {"description":"ZZ-type; degenerate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00228","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00228","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	41
Details	Region: {"description":"Interaction with STH1","evidences":[{"source":"PubMed","id":"9154831","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	2
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine","evidences":[{"source":"UniProtKB","id":"P62807","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P0C1H4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---