Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6KRB

High resolution crystal structure of an Acylphosphatase protein cage

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003998	molecular_function	acylphosphatase activity
A	0016787	molecular_function	hydrolase activity
B	0003998	molecular_function	acylphosphatase activity
B	0016787	molecular_function	hydrolase activity
C	0003998	molecular_function	acylphosphatase activity
C	0016787	molecular_function	hydrolase activity
D	0003998	molecular_function	acylphosphatase activity
D	0016787	molecular_function	hydrolase activity
E	0003998	molecular_function	acylphosphatase activity
E	0016787	molecular_function	hydrolase activity
F	0003998	molecular_function	acylphosphatase activity
F	0016787	molecular_function	hydrolase activity
G	0003998	molecular_function	acylphosphatase activity
G	0016787	molecular_function	hydrolase activity
H	0003998	molecular_function	acylphosphatase activity
H	0016787	molecular_function	hydrolase activity
I	0003998	molecular_function	acylphosphatase activity
I	0016787	molecular_function	hydrolase activity
J	0003998	molecular_function	acylphosphatase activity
J	0016787	molecular_function	hydrolase activity
K	0003998	molecular_function	acylphosphatase activity
K	0016787	molecular_function	hydrolase activity
L	0003998	molecular_function	acylphosphatase activity
L	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue SO4 A 101

Chain	Residue
A	VAL17
A	HOH230
B	HOH224
K	HIS83
A	GLY18
A	PHE19
A	CYS20
A	TYR21
A	HOH205
A	HOH215
A	HOH223
A	HOH225

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 102

Chain	Residue
A	LEU39
A	ASN40
A	SO4103
A	HOH202
A	HOH213

site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 A 103

Chain	Residue
A	ASN40
A	SO4102
A	HOH201
A	HOH202
A	HOH216

site_id	AC4
Number of Residues	7
Details	binding site for residue SO4 A 104

Chain	Residue
A	TYR35
A	LYS37
A	LEU91
A	HOH204
A	HOH206
A	HOH220
F	SO4101

site_id	AC5
Number of Residues	5
Details	binding site for residue GOL A 105

Chain	Residue
A	GLN4
A	SER6
A	LEU55
A	GLU56
A	ARG76

site_id	AC6
Number of Residues	5
Details	binding site for residue SO4 B 101

Chain	Residue
B	TYR35
B	LEU91
B	SO4105
B	HOH212
J	LEU91

site_id	AC7
Number of Residues	11
Details	binding site for residue SO4 B 102

Chain	Residue
B	VAL17
B	GLY18
B	PHE19
B	CYS20
B	TYR21
B	HOH215
B	HOH220
B	HOH235
C	HOH224
I	HIS83
I	HOH211

site_id	AC8
Number of Residues	6
Details	binding site for residue SO4 B 103

Chain	Residue
A	HIS25
A	LYS29
B	HIS25
B	LYS29
C	HIS25
C	LYS29

site_id	AC9
Number of Residues	3
Details	binding site for residue SO4 B 104

Chain	Residue
B	ASN40
B	HOH202
B	HOH205

site_id	AD1
Number of Residues	6
Details	binding site for residue SO4 B 105

Chain	Residue
B	LYS37
B	SO4101
B	HOH206
B	HOH207
I	LYS37
J	LYS37

site_id	AD2
Number of Residues	4
Details	binding site for residue SO4 B 106

Chain	Residue
B	ASN40
B	ASN41
B	HOH202
B	HOH222

site_id	AD3
Number of Residues	4
Details	binding site for residue SO4 C 101

Chain	Residue
C	TYR35
C	LYS37
H	LYS37
H	HOH205

site_id	AD4
Number of Residues	10
Details	binding site for residue SO4 C 102

Chain	Residue
C	VAL17
C	GLY18
C	PHE19
C	CYS20
C	TYR21
C	HOH208
C	HOH216
C	HOH219
C	HOH221
D	HIS83

site_id	AD5
Number of Residues	4
Details	binding site for residue SO4 C 103

Chain	Residue
C	ASN40
C	HOH206
C	HOH209
C	HOH212

site_id	AD6
Number of Residues	4
Details	binding site for residue SO4 C 104

Chain	Residue
C	LYS37
D	LYS37
H	LYS37
H	SO4106

site_id	AD7
Number of Residues	3
Details	binding site for residue SO4 C 105

Chain	Residue
C	ASN40
C	ASN41
C	HOH209

site_id	AD8
Number of Residues	8
Details	binding site for residue GOL C 106

Chain	Residue
I	SER11
I	ARG72
I	GOL107
C	GLN4
C	SER6
C	LEU55
C	GLU56
C	ARG76

site_id	AD9
Number of Residues	3
Details	binding site for residue SO4 D 101

Chain	Residue
C	LYS37
D	TYR35
D	LEU91

site_id	AE1
Number of Residues	11
Details	binding site for residue SO4 D 102

Chain	Residue
D	VAL17
D	GLY18
D	PHE19
D	CYS20
D	TYR21
D	HOH209
D	HOH213
D	HOH221
E	HOH215
H	HIS83
H	HOH216

site_id	AE2
Number of Residues	3
Details	binding site for residue SO4 D 103

Chain	Residue
D	LEU39
D	ASN40
D	SO4104

site_id	AE3
Number of Residues	3
Details	binding site for residue SO4 D 104

Chain	Residue
D	ASN40
D	ASN41
D	SO4103

site_id	AE4
Number of Residues	6
Details	binding site for residue SO4 D 105

Chain	Residue
D	HIS25
D	LYS29
E	HIS25
E	LYS29
F	HIS25
F	LYS29

site_id	AE5
Number of Residues	5
Details	binding site for residue SO4 E 101

Chain	Residue
E	TYR35
E	LYS37
G	LYS37
G	LEU91
G	SO4102

site_id	AE6
Number of Residues	3
Details	binding site for residue SO4 E 102

Chain	Residue
A	GLN4
E	HIS13
E	ARG72

site_id	AE7
Number of Residues	11
Details	binding site for residue SO4 E 103

Chain	Residue
E	VAL17
E	GLY18
E	PHE19
E	CYS20
E	TYR21
E	HOH206
E	HOH209
E	HOH217
F	HOH208
L	HIS83
L	HOH328

site_id	AE8
Number of Residues	4
Details	binding site for residue SO4 E 104

Chain	Residue
E	LEU39
E	ASN40
E	SO4105
E	HOH204

site_id	AE9
Number of Residues	7
Details	binding site for residue SO4 E 105

Chain	Residue
A	ARG76
A	LEU77
A	SER78
E	ASN40
E	ASN41
E	SO4104
E	HOH222

site_id	AF1
Number of Residues	5
Details	binding site for residue SO4 F 101

Chain	Residue
A	SO4104
F	LYS37
F	SO4104
K	LYS37
K	SO4102

site_id	AF2
Number of Residues	4
Details	binding site for residue SO4 F 102

Chain	Residue
F	GLY12
F	HIS13
F	ARG72
L	GLN4

site_id	AF3
Number of Residues	9
Details	binding site for residue SO4 F 103

Chain	Residue
A	HIS83
D	HOH214
F	VAL17
F	GLY18
F	PHE19
F	CYS20
F	TYR21
F	HOH209
F	HOH210

site_id	AF4
Number of Residues	4
Details	binding site for residue SO4 F 104

Chain	Residue
A	HOH204
F	LEU39
F	ASN40
F	SO4101

site_id	AF5
Number of Residues	9
Details	binding site for residue GOL F 105

Chain	Residue
F	SER11
F	ASP43
F	GLN73
F	ARG75
F	HOH201
F	HOH212
L	GLU56
L	TYR59
L	ARG76

site_id	AF6
Number of Residues	2
Details	binding site for residue GOL F 106

Chain	Residue
F	ARG76
F	HOH214

site_id	AF7
Number of Residues	4
Details	binding site for residue SO4 G 101

Chain	Residue
G	TYR35
G	LEU91
G	SO4102
L	LEU91

site_id	AF8
Number of Residues	7
Details	binding site for residue SO4 G 102

Chain	Residue
E	LYS37
E	SO4101
G	LYS37
G	SO4101
G	HOH209
L	LYS37
L	SO4201

site_id	AF9
Number of Residues	11
Details	binding site for residue SO4 G 103

Chain	Residue
E	HIS83
E	HOH211
G	VAL17
G	GLY18
G	PHE19
G	CYS20
G	TYR21
G	HOH208
G	HOH215
G	HOH220
H	HOH219

site_id	AG1
Number of Residues	3
Details	binding site for residue SO4 G 104

Chain	Residue
G	LEU39
G	ASN40
G	HOH202

site_id	AG2
Number of Residues	4
Details	binding site for residue SO4 G 105

Chain	Residue
E	HOH225
G	ASN40
G	ASN41
G	HOH207

site_id	AG3
Number of Residues	5
Details	binding site for residue SO4 H 101

Chain	Residue
D	LYS37
D	LEU91
H	TYR35
H	LYS37
H	LEU91

site_id	AG4
Number of Residues	7
Details	binding site for residue SO4 H 102

Chain	Residue
H	SER11
H	ASP43
H	ARG75
J	GLU56
J	TYR59
J	ARG76
J	GOL105

site_id	AG5
Number of Residues	5
Details	binding site for residue SO4 H 103

Chain	Residue
H	HIS13
H	ARG72
H	HOH221
J	GLN4
J	GOL105

site_id	AG6
Number of Residues	6
Details	binding site for residue SO4 H 104

Chain	Residue
G	HIS25
G	LYS29
H	HIS25
H	LYS29
I	HIS25
I	LYS29

site_id	AG7
Number of Residues	10
Details	binding site for residue SO4 H 105

Chain	Residue
C	HIS83
H	VAL17
H	GLY18
H	PHE19
H	CYS20
H	TYR21
H	HOH209
H	HOH214
H	HOH217
I	HOH220

site_id	AG8
Number of Residues	5
Details	binding site for residue SO4 H 106

Chain	Residue
C	SO4104
H	LEU39
H	ASN40
H	SO4107
H	HOH205

site_id	AG9
Number of Residues	7
Details	binding site for residue SO4 H 107

Chain	Residue
C	LYS7
C	HOH241
H	ASN40
H	ASN41
H	SO4106
J	LEU77
J	SER78

site_id	AH1
Number of Residues	6
Details	binding site for residue SO4 I 101

Chain	Residue
B	LYS37
B	LEU91
B	HOH205
I	TYR35
I	LYS37
I	LEU91

site_id	AH2
Number of Residues	5
Details	binding site for residue SO4 I 102

Chain	Residue
I	LYS37
I	LEU91
I	HOH202
J	TYR35
J	HOH207

site_id	AH3
Number of Residues	4
Details	binding site for residue SO4 I 103

Chain	Residue
C	GLN4
I	GLY12
I	HIS13
I	ARG72

site_id	AH4
Number of Residues	11
Details	binding site for residue SO4 I 104

Chain	Residue
G	HOH219
I	VAL17
I	GLY18
I	PHE19
I	CYS20
I	TYR21
I	HOH214
I	HOH216
I	HOH218
I	HOH225
J	HIS83

site_id	AH5
Number of Residues	6
Details	binding site for residue SO4 I 105

Chain	Residue
B	HOH207
I	LEU39
I	ASN40
I	SO4106
I	HOH202
I	HOH210

site_id	AH6
Number of Residues	7
Details	binding site for residue SO4 I 106

Chain	Residue
C	LEU77
C	SER78
I	ASN40
I	ASN41
I	SO4105
I	HOH210
I	HOH217

site_id	AH7
Number of Residues	10
Details	binding site for residue GOL I 107

Chain	Residue
C	PHE8
C	GLU56
C	TYR59
C	ARG76
C	GOL106
I	SER11
I	ASP43
I	HOH201
I	HOH206
I	HOH208

site_id	AH8
Number of Residues	3
Details	binding site for residue GOL I 108

Chain	Residue
I	TYR59
I	VAL74
I	ARG76

site_id	AH9
Number of Residues	10
Details	binding site for residue SO4 J 101

Chain	Residue
B	HIS83
B	HOH226
J	GLY18
J	PHE19
J	CYS20
J	TYR21
J	HOH212
J	HOH214
J	HOH222
K	HOH223

site_id	AI1
Number of Residues	6
Details	binding site for residue SO4 J 102

Chain	Residue
J	HIS25
J	LYS29
K	HIS25
K	LYS29
L	HIS25
L	LYS29

site_id	AI2
Number of Residues	5
Details	binding site for residue SO4 J 103

Chain	Residue
B	LYS7
J	LEU39
J	ASN40
J	SO4104
J	HOH209

site_id	AI3
Number of Residues	5
Details	binding site for residue SO4 J 104

Chain	Residue
J	ASN40
J	ASN41
J	SO4103
J	HOH205
J	HOH209

site_id	AI4
Number of Residues	9
Details	binding site for residue GOL J 105

Chain	Residue
H	GLY12
H	ARG72
H	SO4102
H	SO4103
J	GLN4
J	SER6
J	LEU55
J	GLU56
J	ARG76

site_id	AI5
Number of Residues	3
Details	binding site for residue SO4 K 101

Chain	Residue
F	LYS37
K	LEU91
K	HOH204

site_id	AI6
Number of Residues	4
Details	binding site for residue SO4 K 102

Chain	Residue
A	LEU91
F	SO4101
K	TYR35
K	LEU91

site_id	AI7
Number of Residues	9
Details	binding site for residue SO4 K 103

Chain	Residue
F	HIS83
K	VAL17
K	GLY18
K	PHE19
K	CYS20
K	TYR21
K	HOH211
K	HOH218
L	HOH314

site_id	AI8
Number of Residues	3
Details	binding site for residue SO4 K 104

Chain	Residue
K	ASN40
K	HOH202
K	HOH209

site_id	AI9
Number of Residues	6
Details	binding site for residue SO4 K 105

Chain	Residue
K	ASN40
K	ASN41
K	HOH202
K	HOH214
K	HOH229
K	HOH239

site_id	AJ1
Number of Residues	5
Details	binding site for residue SO4 L 201

Chain	Residue
E	HOH204
G	SO4102
L	TYR35
L	LYS37
L	HOH306

site_id	AJ2
Number of Residues	11
Details	binding site for residue SO4 L 202

Chain	Residue
G	HIS83
J	HOH208
L	GLY16
L	VAL17
L	GLY18
L	PHE19
L	CYS20
L	TYR21
L	HOH308
L	HOH309
L	HOH318

site_id	AJ3
Number of Residues	4
Details	binding site for residue SO4 L 203

Chain	Residue
L	LEU39
L	ASN40
L	SO4204
L	HOH315

site_id	AJ4
Number of Residues	4
Details	binding site for residue SO4 L 204

Chain	Residue
L	ASN40
L	ASN41
L	SO4203
L	HOH315

Functional Information from PROSITE/UniProt

site_id	PS00151
Number of Residues	17
Details	ACYLPHOSPHATASE_2 Acylphosphatase signature 2. GYAKNlnnGdVevvacG

Chain	Residue	Details
A	GLY34-GLY50

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	ACT_SITE: ACT_SITE => ECO:0000255\|PROSITE-ProRule:PRU00520

Chain	Residue	Details
A	ASN38
B	ASN38
C	ASN38
D	ASN38
E	ASN38
F	ASN38
G	ASN38
H	ASN38
I	ASN38
J	ASN38
K	ASN38
L	ASN38

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)