Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6KPE

343 K cryoEM structure of Sso-KARI in complex with Mg2+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004455	molecular_function	ketol-acid reductoisomerase activity
A	0008652	biological_process	amino acid biosynthetic process
A	0009082	biological_process	branched-chain amino acid biosynthetic process
A	0009097	biological_process	isoleucine biosynthetic process
A	0009099	biological_process	L-valine biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
B	0004455	molecular_function	ketol-acid reductoisomerase activity
B	0008652	biological_process	amino acid biosynthetic process
B	0009082	biological_process	branched-chain amino acid biosynthetic process
B	0009097	biological_process	isoleucine biosynthetic process
B	0009099	biological_process	L-valine biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
C	0004455	molecular_function	ketol-acid reductoisomerase activity
C	0008652	biological_process	amino acid biosynthetic process
C	0009082	biological_process	branched-chain amino acid biosynthetic process
C	0009097	biological_process	isoleucine biosynthetic process
C	0009099	biological_process	L-valine biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
D	0004455	molecular_function	ketol-acid reductoisomerase activity
D	0008652	biological_process	amino acid biosynthetic process
D	0009082	biological_process	branched-chain amino acid biosynthetic process
D	0009097	biological_process	isoleucine biosynthetic process
D	0009099	biological_process	L-valine biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
E	0004455	molecular_function	ketol-acid reductoisomerase activity
E	0008652	biological_process	amino acid biosynthetic process
E	0009082	biological_process	branched-chain amino acid biosynthetic process
E	0009097	biological_process	isoleucine biosynthetic process
E	0009099	biological_process	L-valine biosynthetic process
E	0016491	molecular_function	oxidoreductase activity
F	0004455	molecular_function	ketol-acid reductoisomerase activity
F	0008652	biological_process	amino acid biosynthetic process
F	0009082	biological_process	branched-chain amino acid biosynthetic process
F	0009097	biological_process	isoleucine biosynthetic process
F	0009099	biological_process	L-valine biosynthetic process
F	0016491	molecular_function	oxidoreductase activity
G	0004455	molecular_function	ketol-acid reductoisomerase activity
G	0008652	biological_process	amino acid biosynthetic process
G	0009082	biological_process	branched-chain amino acid biosynthetic process
G	0009097	biological_process	isoleucine biosynthetic process
G	0009099	biological_process	L-valine biosynthetic process
G	0016491	molecular_function	oxidoreductase activity
H	0004455	molecular_function	ketol-acid reductoisomerase activity
H	0008652	biological_process	amino acid biosynthetic process
H	0009082	biological_process	branched-chain amino acid biosynthetic process
H	0009097	biological_process	isoleucine biosynthetic process
H	0009099	biological_process	L-valine biosynthetic process
H	0016491	molecular_function	oxidoreductase activity
I	0004455	molecular_function	ketol-acid reductoisomerase activity
I	0008652	biological_process	amino acid biosynthetic process
I	0009082	biological_process	branched-chain amino acid biosynthetic process
I	0009097	biological_process	isoleucine biosynthetic process
I	0009099	biological_process	L-valine biosynthetic process
I	0016491	molecular_function	oxidoreductase activity
J	0004455	molecular_function	ketol-acid reductoisomerase activity
J	0008652	biological_process	amino acid biosynthetic process
J	0009082	biological_process	branched-chain amino acid biosynthetic process
J	0009097	biological_process	isoleucine biosynthetic process
J	0009099	biological_process	L-valine biosynthetic process
J	0016491	molecular_function	oxidoreductase activity
K	0004455	molecular_function	ketol-acid reductoisomerase activity
K	0008652	biological_process	amino acid biosynthetic process
K	0009082	biological_process	branched-chain amino acid biosynthetic process
K	0009097	biological_process	isoleucine biosynthetic process
K	0009099	biological_process	L-valine biosynthetic process
K	0016491	molecular_function	oxidoreductase activity
L	0004455	molecular_function	ketol-acid reductoisomerase activity
L	0008652	biological_process	amino acid biosynthetic process
L	0009082	biological_process	branched-chain amino acid biosynthetic process
L	0009097	biological_process	isoleucine biosynthetic process
L	0009099	biological_process	L-valine biosynthetic process
L	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue MG A 401

Chain	Residue
A	ASP191
A	GLU195

site_id	AC2
Number of Residues	2
Details	binding site for residue MG B 401

Chain	Residue
B	ASP191
B	GLU195

site_id	AC3
Number of Residues	2
Details	binding site for residue MG C 401

Chain	Residue
C	ASP191
C	GLU195

site_id	AC4
Number of Residues	2
Details	binding site for residue MG D 401

Chain	Residue
D	ASP191
D	GLU195

site_id	AC5
Number of Residues	2
Details	binding site for residue MG E 401

Chain	Residue
E	GLU195
E	ASP191

site_id	AC6
Number of Residues	2
Details	binding site for residue MG F 401

Chain	Residue
F	ASP191
F	GLU195

site_id	AC7
Number of Residues	2
Details	binding site for residue MG G 401

Chain	Residue
G	ASP191
G	GLU195

site_id	AC8
Number of Residues	2
Details	binding site for residue MG H 401

Chain	Residue
H	ASP191
H	GLU195

site_id	AC9
Number of Residues	2
Details	binding site for residue MG I 401

Chain	Residue
I	ASP191
I	GLU195

site_id	AD1
Number of Residues	2
Details	binding site for residue MG J 401

Chain	Residue
J	ASP191
J	GLU195

site_id	AD2
Number of Residues	2
Details	binding site for residue MG K 401

Chain	Residue
K	ASP191
K	GLU195

site_id	AD3
Number of Residues	2
Details	binding site for residue MG L 401

Chain	Residue
L	ASP191
L	GLU195

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1752
Details	Domain: {"description":"KARI C-terminal knotted","evidences":[{"source":"PROSITE-ProRule","id":"PRU01198","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)