6KP5
crystal structure of Xanthine-guanine phosphoribosyltransferase (XGPRT) from Yersinia pestis in P21212 space group with sulphate ions in the active site
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0000310 | molecular_function | xanthine phosphoribosyltransferase activity |
| A | 0004422 | molecular_function | hypoxanthine phosphoribosyltransferase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006166 | biological_process | purine ribonucleoside salvage |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0032263 | biological_process | GMP salvage |
| A | 0032264 | biological_process | IMP salvage |
| A | 0032265 | biological_process | XMP salvage |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052657 | molecular_function | guanine phosphoribosyltransferase activity |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0000310 | molecular_function | xanthine phosphoribosyltransferase activity |
| B | 0004422 | molecular_function | hypoxanthine phosphoribosyltransferase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006166 | biological_process | purine ribonucleoside salvage |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0032263 | biological_process | GMP salvage |
| B | 0032264 | biological_process | IMP salvage |
| B | 0032265 | biological_process | XMP salvage |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0052657 | molecular_function | guanine phosphoribosyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | ARG37 |
| A | GLY38 |
| A | HOH306 |
| B | ARG53 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 202 |
| Chain | Residue |
| A | HOH301 |
| A | ASP92 |
| A | THR93 |
| A | GLY94 |
| A | GLY95 |
| A | THR96 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 201 |
| Chain | Residue |
| B | ASP92 |
| B | THR93 |
| B | GLY94 |
| B | GLY95 |
| B | THR96 |
| B | HOH338 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 202 |
| Chain | Residue |
| A | ARG53 |
| B | ARG37 |
| B | GLY38 |
| B | LYS106 |
| B | HOH301 |
| B | HOH324 |
Functional Information from PROSITE/UniProt
| site_id | PS00103 |
| Number of Residues | 13 |
| Details | PUR_PYR_PR_TRANSFER Purine/pyrimidine phosphoribosyl transferases signature. FIVIDDLVDTGgT |
| Chain | Residue | Details |
| A | PHE84-THR96 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01903 |
| Chain | Residue | Details |
| A | ARG37 | |
| B | ILE135 | |
| A | ASP88 | |
| A | ASP89 | |
| A | ASP92 | |
| A | ILE135 | |
| B | ARG37 | |
| B | ASP88 | |
| B | ASP89 | |
| B | ASP92 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|Ref.4, ECO:0007744|PDB:5XTK |
| Chain | Residue | Details |
| A | ARG69 | |
| A | TRP134 | |
| B | ARG69 | |
| B | TRP134 |
