6KMT
P32 of caspase-11 mutant C254A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
| C | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008234 | molecular_function | cysteine-type peptidase activity |
| D | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PROSITE/UniProt
| site_id | PS01121 |
| Number of Residues | 15 |
| Details | CASPASE_HIS Caspase family histidine active site. HqtsdStfLvLMSHG |
| Chain | Residue | Details |
| A | HIS193-GLY207 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P29466 |
| Chain | Residue | Details |
| A | HIS206 | |
| B | HIS206 | |
| C | HIS206 | |
| D | HIS206 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P49662 |
| Chain | Residue | Details |
| A | ALA254 | |
| B | ALA254 | |
| C | ALA254 | |
| D | ALA254 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:30135078 |
| Chain | Residue | Details |
| A | ASP285 | |
| B | ASP285 | |
| C | ASP285 | |
| D | ASP285 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: (Microbial infection) ADP-riboxanated arginine => ECO:0000269|PubMed:34671164 |
| Chain | Residue | Details |
| A | ARG310 | |
| B | ARG310 | |
| C | ARG310 | |
| D | ARG310 |
