6KMN

Crystal Structure of Dye Decolorizing peroxidase from Bacillus subtilis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004325	molecular_function	ferrochelatase activity
A	0004601	molecular_function	peroxidase activity
A	0005576	cellular_component	extracellular region
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016829	molecular_function	lyase activity
A	0020037	molecular_function	heme binding
A	0033212	biological_process	iron import into cell
A	0046872	molecular_function	metal ion binding
A	0098869	biological_process	cellular oxidant detoxification
B	0004325	molecular_function	ferrochelatase activity
B	0004601	molecular_function	peroxidase activity
B	0005576	cellular_component	extracellular region
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0016491	molecular_function	oxidoreductase activity
B	0016829	molecular_function	lyase activity
B	0020037	molecular_function	heme binding
B	0033212	biological_process	iron import into cell
B	0046872	molecular_function	metal ion binding
B	0098869	biological_process	cellular oxidant detoxification
C	0004325	molecular_function	ferrochelatase activity
C	0004601	molecular_function	peroxidase activity
C	0005576	cellular_component	extracellular region
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0016491	molecular_function	oxidoreductase activity
C	0016829	molecular_function	lyase activity
C	0020037	molecular_function	heme binding
C	0033212	biological_process	iron import into cell
C	0046872	molecular_function	metal ion binding
C	0098869	biological_process	cellular oxidant detoxification
D	0004325	molecular_function	ferrochelatase activity
D	0004601	molecular_function	peroxidase activity
D	0005576	cellular_component	extracellular region
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0016491	molecular_function	oxidoreductase activity
D	0016829	molecular_function	lyase activity
D	0020037	molecular_function	heme binding
D	0033212	biological_process	iron import into cell
D	0046872	molecular_function	metal ion binding
D	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	binding site for residue HEM A 401

Chain	Residue
A	ASN181
A	LYS278
A	ARG286
A	LEU306
A	PHE308
A	MET322
A	LEU326
A	LEU332
A	OXY402
A	HOH513
A	HOH524
A	PHE185
A	HOH619
A	LYS186
A	GLY188
A	THR189
A	GLY190
A	MET227
A	PHE244
A	HIS273

---

site_id	AC2
Number of Residues	3
Details	binding site for residue OXY A 402

Chain	Residue
A	ASP187
A	ARG286
A	HEM401

---

site_id	AC3
Number of Residues	2
Details	binding site for residue CL A 404

Chain	Residue
A	MET302
C	HOH611

---

site_id	AC4
Number of Residues	21
Details	binding site for residue HEM B 401

Chain	Residue
B	ASN181
B	PHE185
B	LYS186
B	ASP187
B	GLY188
B	THR189
B	GLY190
B	ILE225
B	MET227
B	PHE244
B	HIS273
B	ALA277
B	LYS278
B	ARG286
B	LEU306
B	PHE308
B	PHE319
B	MET322
B	LEU326
B	LEU332
B	OXY402

---

site_id	AC5
Number of Residues	3
Details	binding site for residue OXY B 402

Chain	Residue
B	ASP187
B	ARG286
B	HEM401

---

site_id	AC6
Number of Residues	9
Details	binding site for residue GOL B 403

Chain	Residue
B	ILE225
B	SER327
B	ASN333
B	THR336
B	THR338
B	HOH505
B	HOH515
B	HOH526
B	HOH548

---

site_id	AC7
Number of Residues	7
Details	binding site for residue MPD B 404

Chain	Residue
B	ALA118
B	MET119
B	PRO120
D	PRO7
D	TYR9
D	LYS352
D	HOH579

---

site_id	AC8
Number of Residues	20
Details	binding site for residue HEM C 401

Chain	Residue
C	ASN181
C	PHE185
C	LYS186
C	GLY188
C	THR189
C	GLY190
C	MET227
C	PHE244
C	ARG246
C	HIS273
C	ALA277
C	LYS278
C	ARG286
C	LEU306
C	PHE308
C	MET322
C	LEU326
C	LEU332
C	OXY402
C	HOH501

---

site_id	AC9
Number of Residues	4
Details	binding site for residue OXY C 402

Chain	Residue
C	ASP187
C	ARG286
C	PHE308
C	HEM401

---

site_id	AD1
Number of Residues	18
Details	binding site for residue HEM D 401

Chain	Residue
D	HIS273
D	ARG286
D	LEU306
D	PHE308
D	LEU326
D	LEU332
D	OXY402
D	HOH521
D	ASN181
D	PHE185
D	LYS186
D	ASP187
D	GLY188
D	THR189
D	GLY190
D	ILE225
D	MET227
D	PHE244

---

site_id	AD2
Number of Residues	4
Details	binding site for residue OXY D 402

Chain	Residue
D	ASP187
D	ARG286
D	PHE308
D	HEM401

---

site_id	AD3
Number of Residues	2
Details	binding site for residue CL D 403

Chain	Residue
D	LYS351
D	LYS352

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	100
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"32971035","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36345957","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6KMN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7E5Q","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"description":"proximal binding residue","evidences":[{"source":"PubMed","id":"32971035","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36345957","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6KMM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6KMN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7E5Q","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"32971035","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36345957","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6KMM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6KMN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7E5Q","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---