6KKK
Crystal structure of Drug:Proton Antiporter-1 (DHA1) Family SotB, in the inward open conformation (H115A mutant)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008643 | biological_process | carbohydrate transport |
| A | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0034219 | biological_process | carbohydrate transmembrane transport |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0008643 | biological_process | carbohydrate transport |
| B | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| B | 0022857 | molecular_function | transmembrane transporter activity |
| B | 0034219 | biological_process | carbohydrate transmembrane transport |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0008643 | biological_process | carbohydrate transport |
| C | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| C | 0022857 | molecular_function | transmembrane transporter activity |
| C | 0034219 | biological_process | carbohydrate transmembrane transport |
| C | 0055085 | biological_process | transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 240 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET1-ARG14 | |
| B | SER124-ARG135 | |
| B | LEU191-ARG208 | |
| B | LYS267-SER274 | |
| B | GLN320-ASP332 | |
| B | ARG385-GLN396 | |
| C | MET1-ARG14 | |
| C | MET71-LEU80 | |
| C | SER124-ARG135 | |
| C | LEU191-ARG208 | |
| C | LYS267-SER274 | |
| A | MET71-LEU80 | |
| C | GLN320-ASP332 | |
| C | ARG385-GLN396 | |
| A | SER124-ARG135 | |
| A | LEU191-ARG208 | |
| A | LYS267-SER274 | |
| A | GLN320-ASP332 | |
| A | ARG385-GLN396 | |
| B | MET1-ARG14 | |
| B | MET71-LEU80 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 720 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL15-LEU35 | |
| A | ILE299-MET319 | |
| A | VAL333-GLY353 | |
| A | MET364-PHE384 | |
| B | VAL15-LEU35 | |
| B | VAL50-LEU70 | |
| B | LEU81-PHE101 | |
| B | VAL103-ALA123 | |
| B | ALA136-LEU156 | |
| B | PHE170-LEU190 | |
| B | PRO209-TYR229 | |
| A | VAL50-LEU70 | |
| B | PHE246-GLY266 | |
| B | ALA275-ALA295 | |
| B | ILE299-MET319 | |
| B | VAL333-GLY353 | |
| B | MET364-PHE384 | |
| C | VAL15-LEU35 | |
| C | VAL50-LEU70 | |
| C | LEU81-PHE101 | |
| C | VAL103-ALA123 | |
| C | ALA136-LEU156 | |
| A | LEU81-PHE101 | |
| C | PHE170-LEU190 | |
| C | PRO209-TYR229 | |
| C | PHE246-GLY266 | |
| C | ALA275-ALA295 | |
| C | ILE299-MET319 | |
| C | VAL333-GLY353 | |
| C | MET364-PHE384 | |
| A | VAL103-ALA123 | |
| A | ALA136-LEU156 | |
| A | PHE170-LEU190 | |
| A | PRO209-TYR229 | |
| A | PHE246-GLY266 | |
| A | ALA275-ALA295 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 156 |
| Details | TOPO_DOM: Periplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU36-GLN49 | |
| B | SER230-ASN245 | |
| B | ASN296-GLU298 | |
| B | ASN354-SER363 | |
| C | LEU36-GLN49 | |
| C | THR102 | |
| C | GLY157-THR169 | |
| C | SER230-ASN245 | |
| C | ASN296-GLU298 | |
| C | ASN354-SER363 | |
| A | THR102 | |
| A | GLY157-THR169 | |
| A | SER230-ASN245 | |
| A | ASN296-GLU298 | |
| A | ASN354-SER363 | |
| B | LEU36-GLN49 | |
| B | THR102 | |
| B | GLY157-THR169 |
