Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue D8F A 401 |
| Chain | Residue |
| A | TYR38 |
| A | HOH501 |
| A | HOH519 |
| A | HOH538 |
| A | GLY90 |
| A | GLY91 |
| A | SER162 |
| A | ALA163 |
| A | LEU193 |
| A | LEU212 |
| A | PHE220 |
| A | HIS284 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | PRO24 |
| A | HOH538 |
| A | HOH548 |
| A | HOH573 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 403 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | GLU51 |
| A | LEU52 |
| A | HOH517 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | ARG302 |
| A | HOH539 |
| A | HOH734 |
| B | MET309 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | LYS265 |
| A | HOH574 |
| B | GLU269 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | ASP112 |
| A | HOH612 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 408 |
| Chain | Residue |
| A | LEU193 |
| A | ASP196 |
| A | ALA197 |
| A | VAL198 |
| A | ASP221 |
| A | ARG228 |
| A | HOH502 |
| A | HOH519 |
| A | HOH561 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 409 |
| Chain | Residue |
| A | ARG257 |
| A | ARG261 |
| A | GOL410 |
| A | HOH564 |
| A | HOH681 |
| B | HOH513 |
| B | HOH562 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 410 |
| Chain | Residue |
| A | ARG257 |
| A | GOL409 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 411 |
| Chain | Residue |
| A | ARG140 |
| A | PRO179 |
| A | ALA180 |
| A | ASP181 |
| A | HOH552 |
| A | HOH713 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 412 |
| Chain | Residue |
| A | PRO124 |
| A | THR222 |
| A | ALA223 |
| A | HOH513 |
| A | HOH607 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue 6NA A 413 |
| Chain | Residue |
| A | ASP96 |
| A | ASP119 |
| A | TYR120 |
| A | ARG121 |
| A | HOH525 |
| A | HOH534 |
| A | HOH547 |
| A | HOH554 |
| A | HOH679 |
| A | HOH703 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 402 |
| Chain | Residue |
| B | GLU79 |
| B | ALA80 |
| B | HOH501 |
| B | HOH526 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 403 |
| Chain | Residue |
| B | ARG8 |
| B | PRO9 |
| B | ASP10 |
| B | HOH614 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 404 |
| Chain | Residue |
| B | ALA201 |
| B | ALA205 |
| B | ARG257 |
| B | GOL405 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 405 |
| Chain | Residue |
| A | HOH532 |
| B | ARG257 |
| B | ARG261 |
| B | GOL404 |
| B | HOH519 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 406 |
| Chain | Residue |
| B | ASP196 |
| B | ALA197 |
| B | VAL198 |
| B | ILE217 |
| B | ASP221 |
| B | ARG228 |
| B | HOH645 |
| B | HOH662 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 402 |
| Chain | Residue |
| C | ALA64 |
| C | GLY65 |
| C | ASP66 |
| C | HOH624 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 403 |
| Chain | Residue |
| C | HOH683 |
| C | HOH790 |
| C | ARG228 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 404 |
| Chain | Residue |
| C | MET309 |
| C | GLY312 |
| C | HOH501 |
| D | ALA305 |
| site_id | AE4 |
| Number of Residues | 10 |
| Details | binding site for residue GOL C 405 |
| Chain | Residue |
| C | LEU193 |
| C | ASP196 |
| C | ALA197 |
| C | VAL198 |
| C | ILE217 |
| C | ASP221 |
| C | ARG228 |
| C | HOH511 |
| C | HOH573 |
| C | HOH632 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 406 |
| Chain | Residue |
| C | ARG257 |
| C | ARG261 |
| C | GOL407 |
| C | HOH503 |
| D | HOH582 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue GOL C 407 |
| Chain | Residue |
| C | ARG257 |
| C | GOL406 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 408 |
| Chain | Residue |
| C | ARG75 |
| C | GLU76 |
| C | SER77 |
| site_id | AE8 |
| Number of Residues | 8 |
| Details | binding site for residue 6NA C 409 |
| Chain | Residue |
| C | ASP96 |
| C | ASP119 |
| C | TYR120 |
| C | ARG121 |
| C | LEU122 |
| C | HOH543 |
| C | HOH578 |
| C | HOH838 |
| site_id | AE9 |
| Number of Residues | 7 |
| Details | binding site for residue PGE C 410 |
| Chain | Residue |
| C | LYS265 |
| C | ALA266 |
| C | HOH597 |
| C | HOH619 |
| C | HOH708 |
| D | LYS265 |
| D | ALA266 |
| site_id | AF1 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 D 402 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 403 |
| Chain | Residue |
| D | ARG8 |
| D | PRO9 |
| D | ASP10 |
| D | SER295 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 404 |
| Chain | Residue |
| D | LEU122 |
| D | HIS126 |
| D | EDO405 |
| D | HOH703 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 405 |
| Chain | Residue |
| D | ASP119 |
| D | TYR120 |
| D | EDO404 |
| D | HOH503 |
| D | HOH624 |
| site_id | AF5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL D 406 |
| Chain | Residue |
| D | LEU193 |
| D | ASP196 |
| D | ALA197 |
| D | VAL198 |
| D | ILE217 |
| D | ASP221 |
| D | ARG228 |
| D | HOH584 |
| D | HOH592 |
| site_id | AF6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 407 |
| Chain | Residue |
| C | HOH544 |
| C | HOH588 |
| D | ARG257 |
| D | ARG261 |
| D | GOL408 |
| D | HOH508 |
| D | HOH654 |
| site_id | AF7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 408 |
| Chain | Residue |
| D | ALA201 |
| D | ALA205 |
| D | ARG257 |
| D | GOL407 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 409 |
| Chain | Residue |
| D | ALA74 |
| D | ASP112 |
| D | HOH553 |
| D | HOH631 |
| site_id | AF9 |
| Number of Residues | 6 |
| Details | binding site for residue NPO D 410 |
| Chain | Residue |
| D | LYS12 |
| D | LEU15 |
| D | GLU16 |
| D | GLY209 |
| D | PHE210 |
| D | HOH782 |
| site_id | AG1 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide D8F B 401 and SER B 162 |
| Chain | Residue |
| B | GLY90 |
| B | GLY91 |
| B | ASP161 |
| B | ALA163 |
| B | GLY164 |
| B | GLY165 |
| B | ASN166 |
| B | ILE190 |
| B | PHE191 |
| B | PRO192 |
| B | LEU212 |
| B | HIS284 |
| B | HOH645 |
| site_id | AG2 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide D8F C 401 and SER C 162 |
| Chain | Residue |
| C | TYR38 |
| C | GLY90 |
| C | GLY91 |
| C | ASP161 |
| C | ALA163 |
| C | GLY164 |
| C | GLY165 |
| C | ASN166 |
| C | ILE190 |
| C | PHE191 |
| C | PRO192 |
| C | LEU212 |
| C | PHE220 |
| C | HIS284 |
| C | HOH748 |
| site_id | AG3 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide D8F D 401 and SER D 162 |
| Chain | Residue |
| D | TYR38 |
| D | GLY89 |
| D | GLY90 |
| D | GLY91 |
| D | ASP161 |
| D | ALA163 |
| D | GLY164 |
| D | GLY165 |
| D | ASN166 |
| D | ILE190 |
| D | PHE191 |
| D | LEU193 |
| D | LEU212 |
| D | HIS284 |
| D | HOH584 |
