6KDS

Crystal structure of human NRMT2 in complex with alpha-N-monomethylated human CENP-A peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006480	biological_process	N-terminal protein amino acid methylation
A	0008168	molecular_function	methyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	binding site for residue SAH A 501

Chain	Residue
A	TYR76
A	TYR172
A	SER173
A	LEU174
A	GLN175
A	GLN190
A	TRP191
A	VAL192
A	HIS195
A	HOH654
A	HOH658
A	GLY124
A	SER125
A	GLY126
A	ARG129
A	ASP146
A	MET147
A	MET148
A	PHE151

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N,N,N-trimethylglycine => ECO:0000269|PubMed:23818633, ECO:0000269|PubMed:26543159

Chain	Residue	Details
E	SAR1
A	ARG129
A	ASP146
A	LEU174
A	HIS195

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine; by AURKA and AURKB => ECO:0000269|PubMed:11756469, ECO:0000269|PubMed:14667408, ECO:0000269|PubMed:18239465

Chain	Residue	Details
E	SER6

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