Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004032 | molecular_function | aldose reductase (NADPH) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue CAC A 401 |
| Chain | Residue |
| A | TRP24 |
| A | TYR52 |
| A | HIS114 |
| A | ASN159 |
| A | TYR206 |
| A | GOL403 |
| A | HOH502 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue ACT A 402 |
| Chain | Residue |
| A | GLU94 |
| A | LYS121 |
| A | LYS256 |
| A | SER257 |
| A | VAL258 |
| A | ARG262 |
| A | GLU90 |
| A | ASP91 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | GLY22 |
| A | THR23 |
| A | TRP24 |
| A | ASP47 |
| A | TYR52 |
| A | GLN180 |
| A | TYR206 |
| A | CAC401 |
| A | HOH539 |
Functional Information from PROSITE/UniProt
| site_id | PS00062 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. MeklydsgkSRAIGVSNF |
| Chain | Residue | Details |
| A | MET143-PHE160 | |
| site_id | PS00063 |
| Number of Residues | 16 |
| Details | ALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. LPKSVSeeRIkQNlDV |
| Chain | Residue | Details |
| A | LEU254-VAL269 | |
| site_id | PS00798 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_1 Aldo/keto reductase family signature 1. GYRHIDCAsaynnEkeVG |
| Chain | Residue | Details |
| A | GLY42-GLY59 | |
