6KA3
Crystal structure of a Thebaine synthase from Papaver somniferum
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006952 | biological_process | defense response |
| A | 0009820 | biological_process | alkaloid metabolic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016835 | molecular_function | carbon-oxygen lyase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| B | 0006952 | biological_process | defense response |
| B | 0009820 | biological_process | alkaloid metabolic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016835 | molecular_function | carbon-oxygen lyase activity |
| B | 0042803 | molecular_function | protein homodimerization activity |
| C | 0006952 | biological_process | defense response |
| C | 0009820 | biological_process | alkaloid metabolic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016835 | molecular_function | carbon-oxygen lyase activity |
| C | 0042803 | molecular_function | protein homodimerization activity |
| D | 0006952 | biological_process | defense response |
| D | 0009820 | biological_process | alkaloid metabolic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0016835 | molecular_function | carbon-oxygen lyase activity |
| D | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | LYS128 |
| A | PRO134 |
| A | THR135 |
| A | HOH301 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue PLM B 200 |
| Chain | Residue |
| B | TYR139 |
| B | LEU140 |
| B | HOH309 |
| B | SER74 |
| B | THR105 |
| B | ARG122 |
| B | SER123 |
| B | ILE124 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue PLM C 200 |
| Chain | Residue |
| C | TRP63 |
| C | SER74 |
| C | HIS89 |
| C | THR105 |
| C | ARG122 |
| C | SER123 |
| C | ILE124 |
| C | TYR139 |
| C | LEU140 |
| C | PHE142 |
| C | GLY143 |
| C | HOH306 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 201 |
| Chain | Residue |
| C | HOH307 |
| D | PRO134 |
| D | THR135 |
| D | HOH323 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000269|PubMed:32703404, ECO:0007744|PDB:6KA3 |
| Chain | Residue | Details |
| A | HIS89 | |
| B | HIS89 | |
| C | HIS89 | |
| D | HIS89 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:32703404, ECO:0007744|PDB:6KA3 |
| Chain | Residue | Details |
| A | SER74 | |
| A | THR105 | |
| B | SER74 | |
| B | THR105 | |
| C | SER74 | |
| C | THR105 | |
| D | SER74 | |
| D | THR105 |
