6K9B
Apo structure of NrS-1 N terminal domain N305
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: For polymerase activity => ECO:0000269|PubMed:28265063 |
| Chain | Residue | Details |
| A | ASP78 | |
| A | ASP80 | |
| A | HIS115 | |
| B | ASP78 | |
| B | ASP80 | |
| B | HIS115 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: For polymerase and primase activities => ECO:0000269|PubMed:30739783 |
| Chain | Residue | Details |
| A | GLU139 | |
| B | GLU139 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31176489, ECO:0000269|PubMed:34975792 |
| Chain | Residue | Details |
| A | ASP78 | |
| A | ASP80 | |
| B | ASP78 | |
| B | ASP80 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:31176489 |
| Chain | Residue | Details |
| A | SER108 | |
| A | HIS115 | |
| B | SER108 | |
| B | HIS115 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:30739783 |
| Chain | Residue | Details |
| A | GLU304 | |
| B | GLU304 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | SITE: Involved in primer extension => ECO:0000269|PubMed:31176489 |
| Chain | Residue | Details |
| A | ARG145 | |
| B | ARG145 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | SITE: Involved in sugar discrimination to select deoxynucleotides => ECO:0000269|PubMed:31176489 |
| Chain | Residue | Details |
| A | TYR146 | |
| B | TYR146 |
