6K8C

Crystal structure of Helicobacter pylori folylpolyglutamate synthetase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004326	molecular_function	tetrahydrofolylpolyglutamate synthase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006761	biological_process	dihydrofolate biosynthetic process
A	0008841	molecular_function	dihydrofolate synthase activity
A	0009058	biological_process	biosynthetic process
A	0009396	biological_process	folic acid-containing compound biosynthetic process
A	0016881	molecular_function	acid-amino acid ligase activity
A	0046654	biological_process	tetrahydrofolate biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0046901	biological_process	tetrahydrofolylpolyglutamate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue CIT A 501

Chain	Residue
A	GLY57
A	HOH620
A	HOH627
A	HOH703
A	HOH766
A	GLY59
A	SER60
A	ARG238
A	ASN243
A	ARG274
A	GLY287
A	HOH601
A	HOH603

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site_id	AC2
Number of Residues	7
Details	binding site for residue GOL A 502

Chain	Residue
A	LYS21
A	GLU22
A	TYR121
A	PHE122
A	HOH616
A	HOH629
A	HOH748

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