6K7X
Human MCU-EMRE complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| B | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| C | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| D | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| E | 0036444 | biological_process | calcium import into the mitochondrion |
| E | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| E | 1990246 | cellular_component | uniplex complex |
| F | 0036444 | biological_process | calcium import into the mitochondrion |
| F | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| F | 1990246 | cellular_component | uniplex complex |
| G | 0036444 | biological_process | calcium import into the mitochondrion |
| G | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| G | 1990246 | cellular_component | uniplex complex |
| H | 0036444 | biological_process | calcium import into the mitochondrion |
| H | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| H | 1990246 | cellular_component | uniplex complex |
| K | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| L | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| M | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| N | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| O | 0036444 | biological_process | calcium import into the mitochondrion |
| O | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| O | 1990246 | cellular_component | uniplex complex |
| P | 0036444 | biological_process | calcium import into the mitochondrion |
| P | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| P | 1990246 | cellular_component | uniplex complex |
| Q | 0036444 | biological_process | calcium import into the mitochondrion |
| Q | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| Q | 1990246 | cellular_component | uniplex complex |
| R | 0036444 | biological_process | calcium import into the mitochondrion |
| R | 0051560 | biological_process | mitochondrial calcium ion homeostasis |
| R | 1990246 | cellular_component | uniplex complex |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 336 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:31080062, ECO:0000269|PubMed:32494073, ECO:0000269|PubMed:32762847, ECO:0000269|PubMed:32862359, ECO:0007744|PDB:6K7X, ECO:0007744|PDB:6K7Y, ECO:0007744|PDB:6O58, ECO:0007744|PDB:6O5B, ECO:0007744|PDB:6WDN, ECO:0007744|PDB:6WDO, ECO:0007744|PDB:6XJV, ECO:0007744|PDB:6XJX |
| Chain | Residue | Details |
| C | LEU234-TRP255 | |
| K | MET263-MET284 | |
| L | LEU234-TRP255 | |
| L | MET263-MET284 | |
| M | LEU234-TRP255 | |
| M | MET263-MET284 | |
| N | LEU234-TRP255 | |
| N | MET263-MET284 | |
| C | MET263-MET284 | |
| A | LEU234-TRP255 | |
| A | MET263-MET284 | |
| B | LEU234-TRP255 | |
| B | MET263-MET284 | |
| D | LEU234-TRP255 | |
| D | MET263-MET284 | |
| K | LEU234-TRP255 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 48 |
| Details | TOPO_DOM: Mitochondrial intermembrane => ECO:0000305|PubMed:27099988, ECO:0000305|PubMed:31080062, ECO:0000305|PubMed:32494073, ECO:0000305|PubMed:32762847 |
| Chain | Residue | Details |
| C | TRP256-ILE262 | |
| A | TRP256-ILE262 | |
| B | TRP256-ILE262 | |
| D | TRP256-ILE262 | |
| K | TRP256-ILE262 | |
| L | TRP256-ILE262 | |
| M | TRP256-ILE262 | |
| N | TRP256-ILE262 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31080062, ECO:0000269|PubMed:32494073, ECO:0000269|PubMed:32862359, ECO:0007744|PDB:6K7X, ECO:0007744|PDB:6K7Y, ECO:0007744|PDB:6O58, ECO:0007744|PDB:6O5B, ECO:0007744|PDB:6WDO |
| Chain | Residue | Details |
| C | GLU264 | |
| A | GLU264 | |
| B | GLU264 | |
| D | GLU264 | |
| K | GLU264 | |
| L | GLU264 | |
| M | GLU264 | |
| N | GLU264 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | MOD_RES: Phosphoserine; by CaMK2 => ECO:0000305|PubMed:23051746 |
| Chain | Residue | Details |
| C | SER92 | |
| A | SER92 | |
| B | SER92 | |
| D | SER92 | |
| K | SER92 | |
| L | SER92 | |
| M | SER92 | |
| N | SER92 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | MOD_RES: S-glutathionyl cysteine => ECO:0000269|PubMed:28262504 |
| Chain | Residue | Details |
| C | CYS97 | |
| A | CYS97 | |
| B | CYS97 | |
| D | CYS97 | |
| K | CYS97 | |
| L | CYS97 | |
| M | CYS97 | |
| N | CYS97 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q3UMR5 |
| Chain | Residue | Details |
| C | LYS332 | |
| A | LYS332 | |
| B | LYS332 | |
| D | LYS332 | |
| K | LYS332 | |
| L | LYS332 | |
| M | LYS332 | |
| N | LYS332 |
