6K6T

Crystal structure of a standalone versatile EAL protein from Vibrio cholerae O395 - c-di-IMP bound form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0046872	molecular_function	metal ion binding
A	0071111	molecular_function	cyclic-guanylate-specific phosphodiesterase activity
B	0000166	molecular_function	nucleotide binding
B	0046872	molecular_function	metal ion binding
B	0071111	molecular_function	cyclic-guanylate-specific phosphodiesterase activity
C	0000166	molecular_function	nucleotide binding
C	0046872	molecular_function	metal ion binding
C	0071111	molecular_function	cyclic-guanylate-specific phosphodiesterase activity
D	0000166	molecular_function	nucleotide binding
D	0046872	molecular_function	metal ion binding
D	0071111	molecular_function	cyclic-guanylate-specific phosphodiesterase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	26
Details	binding site for residue C2I A 501

Chain	Residue
A	GLN31
A	ASP158
A	ASP159
A	MET182
A	GLY216
A	VAL217
A	GLU218
A	GLY236
A	TYR237
A	CA502
A	CA503
A	GLU45
A	HOH620
A	HOH628
A	HOH636
A	HOH645
A	HOH646
A	HOH665
A	HOH670
A	LEU47
A	VAL48
A	ARG49
A	ALA56
A	ILE60
A	CYS75
A	ASN95

---

site_id	AC2
Number of Residues	6
Details	binding site for residue CA A 502

Chain	Residue
A	GLU45
A	ASN95
A	GLU128
A	ASP158
A	C2I501
A	HOH601

---

site_id	AC3
Number of Residues	4
Details	binding site for residue CA A 503

Chain	Residue
A	ASP158
A	ASP159
A	GLU215
A	C2I501

---

site_id	AC4
Number of Residues	24
Details	binding site for residue C2I B 501

Chain	Residue
B	GLN31
B	GLU45
B	LEU47
B	VAL48
B	ARG49
B	ALA56
B	CYS75
B	ASN95
B	ASP158
B	ASP159
B	MET182
B	GLY216
B	VAL217
B	GLU218
B	GLY236
B	TYR237
B	PRO242
B	CA502
B	CA503
B	HOH624
B	HOH635
B	HOH646
B	HOH647
B	HOH650

---

site_id	AC5
Number of Residues	6
Details	binding site for residue CA B 502

Chain	Residue
B	GLU45
B	ASN95
B	GLU128
B	ASP158
B	C2I501
B	HOH601

---

site_id	AC6
Number of Residues	5
Details	binding site for residue CA B 503

Chain	Residue
B	ASP158
B	ASP159
B	GLU215
B	C2I501
B	HOH601

---

site_id	AC7
Number of Residues	22
Details	binding site for residue C2I C 501

Chain	Residue
C	GLN31
C	GLU45
C	LEU47
C	VAL48
C	ARG49
C	ALA56
C	ILE60
C	ASN95
C	ASP158
C	ASP159
C	MET182
C	GLY216
C	VAL217
C	GLU218
C	GLY236
C	TYR237
C	CA502
C	CA503
C	HOH601
C	HOH628
C	HOH640
C	HOH652

---

site_id	AC8
Number of Residues	6
Details	binding site for residue CA C 502

Chain	Residue
C	GLU45
C	ASN95
C	GLU128
C	ASP158
C	C2I501
C	HOH601

---

site_id	AC9
Number of Residues	5
Details	binding site for residue CA C 503

Chain	Residue
C	ASP158
C	ASP159
C	GLU215
C	C2I501
C	HOH601

---

site_id	AD1
Number of Residues	21
Details	binding site for residue C2I D 501

Chain	Residue
D	GLN31
D	GLU45
D	LEU47
D	VAL48
D	ARG49
D	ALA56
D	ILE60
D	CYS75
D	ASN95
D	ASP158
D	ASP159
D	MET182
D	GLY216
D	VAL217
D	GLU218
D	GLY236
D	TYR237
D	PRO242
D	CA502
D	CA503
D	HOH613

---

site_id	AD2
Number of Residues	7
Details	binding site for residue CA D 502

Chain	Residue
D	GLU45
D	ASN95
D	GLU128
D	ASP158
D	C2I501
D	CA503
D	HOH604

---

site_id	AD3
Number of Residues	6
Details	binding site for residue CA D 503

Chain	Residue
D	ASP158
D	ASP159
D	GLU215
D	C2I501
D	CA502
D	HOH604

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