6K5O

Development of Novel Lithocholic Acid Derivatives as Vitamin D Receptor Agonists

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue D0O A 501

Chain	Residue
A	TYR143
A	LEU223
A	VAL230
A	SER271
A	SER274
A	CYS284
A	HIS393
A	VAL414
A	HOH617

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:15065852, ECO:0007744|PDB:1RK3

Chain	Residue	Details
A	TYR143
A	MET280
A	LYS317
A	LEU321
A	VAL348

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