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6K43

Cryo-EM structure of Holo-bacterioferritin-form-I from Streptomyces coelicolor

Functional Information from GO Data
ChainGOidnamespacecontents
A0004322molecular_functionferroxidase activity
A0005506molecular_functioniron ion binding
A0005829cellular_componentcytosol
A0006826biological_processiron ion transport
A0006879biological_processintracellular iron ion homeostasis
A0006880biological_processintracellular sequestering of iron ion
A0008199molecular_functionferric iron binding
A0015093molecular_functionferrous iron transmembrane transporter activity
A0016491molecular_functionoxidoreductase activity
A0020037molecular_functionheme binding
A0034755biological_processiron ion transmembrane transport
A0046872molecular_functionmetal ion binding
B0004322molecular_functionferroxidase activity
B0005506molecular_functioniron ion binding
B0005829cellular_componentcytosol
B0006826biological_processiron ion transport
B0006879biological_processintracellular iron ion homeostasis
B0006880biological_processintracellular sequestering of iron ion
B0008199molecular_functionferric iron binding
B0015093molecular_functionferrous iron transmembrane transporter activity
B0016491molecular_functionoxidoreductase activity
B0020037molecular_functionheme binding
B0034755biological_processiron ion transmembrane transport
B0046872molecular_functionmetal ion binding
C0004322molecular_functionferroxidase activity
C0005506molecular_functioniron ion binding
C0005829cellular_componentcytosol
C0006826biological_processiron ion transport
C0006879biological_processintracellular iron ion homeostasis
C0006880biological_processintracellular sequestering of iron ion
C0008199molecular_functionferric iron binding
C0015093molecular_functionferrous iron transmembrane transporter activity
C0016491molecular_functionoxidoreductase activity
C0020037molecular_functionheme binding
C0034755biological_processiron ion transmembrane transport
C0046872molecular_functionmetal ion binding
D0004322molecular_functionferroxidase activity
D0005506molecular_functioniron ion binding
D0005829cellular_componentcytosol
D0006826biological_processiron ion transport
D0006879biological_processintracellular iron ion homeostasis
D0006880biological_processintracellular sequestering of iron ion
D0008199molecular_functionferric iron binding
D0015093molecular_functionferrous iron transmembrane transporter activity
D0016491molecular_functionoxidoreductase activity
D0020037molecular_functionheme binding
D0034755biological_processiron ion transmembrane transport
D0046872molecular_functionmetal ion binding
E0004322molecular_functionferroxidase activity
E0005506molecular_functioniron ion binding
E0005829cellular_componentcytosol
E0006826biological_processiron ion transport
E0006879biological_processintracellular iron ion homeostasis
E0006880biological_processintracellular sequestering of iron ion
E0008199molecular_functionferric iron binding
E0015093molecular_functionferrous iron transmembrane transporter activity
E0016491molecular_functionoxidoreductase activity
E0020037molecular_functionheme binding
E0034755biological_processiron ion transmembrane transport
E0046872molecular_functionmetal ion binding
F0004322molecular_functionferroxidase activity
F0005506molecular_functioniron ion binding
F0005829cellular_componentcytosol
F0006826biological_processiron ion transport
F0006879biological_processintracellular iron ion homeostasis
F0006880biological_processintracellular sequestering of iron ion
F0008199molecular_functionferric iron binding
F0015093molecular_functionferrous iron transmembrane transporter activity
F0016491molecular_functionoxidoreductase activity
F0020037molecular_functionheme binding
F0034755biological_processiron ion transmembrane transport
F0046872molecular_functionmetal ion binding
G0004322molecular_functionferroxidase activity
G0005506molecular_functioniron ion binding
G0005829cellular_componentcytosol
G0006826biological_processiron ion transport
G0006879biological_processintracellular iron ion homeostasis
G0006880biological_processintracellular sequestering of iron ion
G0008199molecular_functionferric iron binding
G0015093molecular_functionferrous iron transmembrane transporter activity
G0016491molecular_functionoxidoreductase activity
G0020037molecular_functionheme binding
G0034755biological_processiron ion transmembrane transport
G0046872molecular_functionmetal ion binding
H0004322molecular_functionferroxidase activity
H0005506molecular_functioniron ion binding
H0005829cellular_componentcytosol
H0006826biological_processiron ion transport
H0006879biological_processintracellular iron ion homeostasis
H0006880biological_processintracellular sequestering of iron ion
H0008199molecular_functionferric iron binding
H0015093molecular_functionferrous iron transmembrane transporter activity
H0016491molecular_functionoxidoreductase activity
H0020037molecular_functionheme binding
H0034755biological_processiron ion transmembrane transport
H0046872molecular_functionmetal ion binding
I0004322molecular_functionferroxidase activity
I0005506molecular_functioniron ion binding
I0005829cellular_componentcytosol
I0006826biological_processiron ion transport
I0006879biological_processintracellular iron ion homeostasis
I0006880biological_processintracellular sequestering of iron ion
I0008199molecular_functionferric iron binding
I0015093molecular_functionferrous iron transmembrane transporter activity
I0016491molecular_functionoxidoreductase activity
I0020037molecular_functionheme binding
I0034755biological_processiron ion transmembrane transport
I0046872molecular_functionmetal ion binding
J0004322molecular_functionferroxidase activity
J0005506molecular_functioniron ion binding
J0005829cellular_componentcytosol
J0006826biological_processiron ion transport
J0006879biological_processintracellular iron ion homeostasis
J0006880biological_processintracellular sequestering of iron ion
J0008199molecular_functionferric iron binding
J0015093molecular_functionferrous iron transmembrane transporter activity
J0016491molecular_functionoxidoreductase activity
J0020037molecular_functionheme binding
J0034755biological_processiron ion transmembrane transport
J0046872molecular_functionmetal ion binding
K0004322molecular_functionferroxidase activity
K0005506molecular_functioniron ion binding
K0005829cellular_componentcytosol
K0006826biological_processiron ion transport
K0006879biological_processintracellular iron ion homeostasis
K0006880biological_processintracellular sequestering of iron ion
K0008199molecular_functionferric iron binding
K0015093molecular_functionferrous iron transmembrane transporter activity
K0016491molecular_functionoxidoreductase activity
K0020037molecular_functionheme binding
K0034755biological_processiron ion transmembrane transport
K0046872molecular_functionmetal ion binding
L0004322molecular_functionferroxidase activity
L0005506molecular_functioniron ion binding
L0005829cellular_componentcytosol
L0006826biological_processiron ion transport
L0006879biological_processintracellular iron ion homeostasis
L0006880biological_processintracellular sequestering of iron ion
L0008199molecular_functionferric iron binding
L0015093molecular_functionferrous iron transmembrane transporter activity
L0016491molecular_functionoxidoreductase activity
L0020037molecular_functionheme binding
L0034755biological_processiron ion transmembrane transport
L0046872molecular_functionmetal ion binding
M0004322molecular_functionferroxidase activity
M0005506molecular_functioniron ion binding
M0005829cellular_componentcytosol
M0006826biological_processiron ion transport
M0006879biological_processintracellular iron ion homeostasis
M0006880biological_processintracellular sequestering of iron ion
M0008199molecular_functionferric iron binding
M0015093molecular_functionferrous iron transmembrane transporter activity
M0016491molecular_functionoxidoreductase activity
M0020037molecular_functionheme binding
M0034755biological_processiron ion transmembrane transport
M0046872molecular_functionmetal ion binding
N0004322molecular_functionferroxidase activity
N0005506molecular_functioniron ion binding
N0005829cellular_componentcytosol
N0006826biological_processiron ion transport
N0006879biological_processintracellular iron ion homeostasis
N0006880biological_processintracellular sequestering of iron ion
N0008199molecular_functionferric iron binding
N0015093molecular_functionferrous iron transmembrane transporter activity
N0016491molecular_functionoxidoreductase activity
N0020037molecular_functionheme binding
N0034755biological_processiron ion transmembrane transport
N0046872molecular_functionmetal ion binding
O0004322molecular_functionferroxidase activity
O0005506molecular_functioniron ion binding
O0005829cellular_componentcytosol
O0006826biological_processiron ion transport
O0006879biological_processintracellular iron ion homeostasis
O0006880biological_processintracellular sequestering of iron ion
O0008199molecular_functionferric iron binding
O0015093molecular_functionferrous iron transmembrane transporter activity
O0016491molecular_functionoxidoreductase activity
O0020037molecular_functionheme binding
O0034755biological_processiron ion transmembrane transport
O0046872molecular_functionmetal ion binding
P0004322molecular_functionferroxidase activity
P0005506molecular_functioniron ion binding
P0005829cellular_componentcytosol
P0006826biological_processiron ion transport
P0006879biological_processintracellular iron ion homeostasis
P0006880biological_processintracellular sequestering of iron ion
P0008199molecular_functionferric iron binding
P0015093molecular_functionferrous iron transmembrane transporter activity
P0016491molecular_functionoxidoreductase activity
P0020037molecular_functionheme binding
P0034755biological_processiron ion transmembrane transport
P0046872molecular_functionmetal ion binding
Q0004322molecular_functionferroxidase activity
Q0005506molecular_functioniron ion binding
Q0005829cellular_componentcytosol
Q0006826biological_processiron ion transport
Q0006879biological_processintracellular iron ion homeostasis
Q0006880biological_processintracellular sequestering of iron ion
Q0008199molecular_functionferric iron binding
Q0015093molecular_functionferrous iron transmembrane transporter activity
Q0016491molecular_functionoxidoreductase activity
Q0020037molecular_functionheme binding
Q0034755biological_processiron ion transmembrane transport
Q0046872molecular_functionmetal ion binding
R0004322molecular_functionferroxidase activity
R0005506molecular_functioniron ion binding
R0005829cellular_componentcytosol
R0006826biological_processiron ion transport
R0006879biological_processintracellular iron ion homeostasis
R0006880biological_processintracellular sequestering of iron ion
R0008199molecular_functionferric iron binding
R0015093molecular_functionferrous iron transmembrane transporter activity
R0016491molecular_functionoxidoreductase activity
R0020037molecular_functionheme binding
R0034755biological_processiron ion transmembrane transport
R0046872molecular_functionmetal ion binding
S0004322molecular_functionferroxidase activity
S0005506molecular_functioniron ion binding
S0005829cellular_componentcytosol
S0006826biological_processiron ion transport
S0006879biological_processintracellular iron ion homeostasis
S0006880biological_processintracellular sequestering of iron ion
S0008199molecular_functionferric iron binding
S0015093molecular_functionferrous iron transmembrane transporter activity
S0016491molecular_functionoxidoreductase activity
S0020037molecular_functionheme binding
S0034755biological_processiron ion transmembrane transport
S0046872molecular_functionmetal ion binding
T0004322molecular_functionferroxidase activity
T0005506molecular_functioniron ion binding
T0005829cellular_componentcytosol
T0006826biological_processiron ion transport
T0006879biological_processintracellular iron ion homeostasis
T0006880biological_processintracellular sequestering of iron ion
T0008199molecular_functionferric iron binding
T0015093molecular_functionferrous iron transmembrane transporter activity
T0016491molecular_functionoxidoreductase activity
T0020037molecular_functionheme binding
T0034755biological_processiron ion transmembrane transport
T0046872molecular_functionmetal ion binding
U0004322molecular_functionferroxidase activity
U0005506molecular_functioniron ion binding
U0005829cellular_componentcytosol
U0006826biological_processiron ion transport
U0006879biological_processintracellular iron ion homeostasis
U0006880biological_processintracellular sequestering of iron ion
U0008199molecular_functionferric iron binding
U0015093molecular_functionferrous iron transmembrane transporter activity
U0016491molecular_functionoxidoreductase activity
U0020037molecular_functionheme binding
U0034755biological_processiron ion transmembrane transport
U0046872molecular_functionmetal ion binding
V0004322molecular_functionferroxidase activity
V0005506molecular_functioniron ion binding
V0005829cellular_componentcytosol
V0006826biological_processiron ion transport
V0006879biological_processintracellular iron ion homeostasis
V0006880biological_processintracellular sequestering of iron ion
V0008199molecular_functionferric iron binding
V0015093molecular_functionferrous iron transmembrane transporter activity
V0016491molecular_functionoxidoreductase activity
V0020037molecular_functionheme binding
V0034755biological_processiron ion transmembrane transport
V0046872molecular_functionmetal ion binding
W0004322molecular_functionferroxidase activity
W0005506molecular_functioniron ion binding
W0005829cellular_componentcytosol
W0006826biological_processiron ion transport
W0006879biological_processintracellular iron ion homeostasis
W0006880biological_processintracellular sequestering of iron ion
W0008199molecular_functionferric iron binding
W0015093molecular_functionferrous iron transmembrane transporter activity
W0016491molecular_functionoxidoreductase activity
W0020037molecular_functionheme binding
W0034755biological_processiron ion transmembrane transport
W0046872molecular_functionmetal ion binding
X0004322molecular_functionferroxidase activity
X0005506molecular_functioniron ion binding
X0005829cellular_componentcytosol
X0006826biological_processiron ion transport
X0006879biological_processintracellular iron ion homeostasis
X0006880biological_processintracellular sequestering of iron ion
X0008199molecular_functionferric iron binding
X0015093molecular_functionferrous iron transmembrane transporter activity
X0016491molecular_functionoxidoreductase activity
X0020037molecular_functionheme binding
X0034755biological_processiron ion transmembrane transport
X0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue FE2 A 201
ChainResidue
AGLU18
AGLU51
AHIS54
AGLU127

site_idAC2
Number of Residues9
Detailsbinding site for residue HEM A 202
ChainResidue
BASN23
BPHE26
BMET52
BTYR71
ALEU19
AASN23
APHE26
AMET52
BLEU19

site_idAC3
Number of Residues4
Detailsbinding site for residue FE2 B 200
ChainResidue
BGLU18
BGLU51
BHIS54
BGLU127

site_idAC4
Number of Residues4
Detailsbinding site for residue FE2 C 201
ChainResidue
CGLU18
CGLU51
CHIS54
CGLU127

site_idAC5
Number of Residues8
Detailsbinding site for residue HEM C 202
ChainResidue
CPHE26
CPHE49
CMET52
CARG53
CHIS54
CGLU56
DPHE26
DMET52

site_idAC6
Number of Residues4
Detailsbinding site for residue FE2 D 201
ChainResidue
DGLU18
DGLU51
DHIS54
DGLU127

site_idAC7
Number of Residues4
Detailsbinding site for residue FE2 F 201
ChainResidue
FGLU18
FGLU51
FHIS54
FGLU127

site_idAC8
Number of Residues10
Detailsbinding site for residue HEM F 202
ChainResidue
ELEU19
EPHE26
EMET52
ETYR71
FLEU19
FASN23
FARG45
FPHE49
FMET52
FTYR71

site_idAC9
Number of Residues4
Detailsbinding site for residue FE2 E 201
ChainResidue
EGLU18
EGLU51
EHIS54
EGLU127

site_idAD1
Number of Residues4
Detailsbinding site for residue FE2 G 201
ChainResidue
GGLU18
GGLU51
GHIS54
GGLU127

site_idAD2
Number of Residues4
Detailsbinding site for residue FE2 H 201
ChainResidue
HGLU18
HGLU51
HHIS54
HGLU127

site_idAD3
Number of Residues4
Detailsbinding site for residue FE2 I 201
ChainResidue
IGLU18
IGLU51
IHIS54
IGLU127

site_idAD4
Number of Residues4
Detailsbinding site for residue FE2 J 201
ChainResidue
JGLU18
JGLU51
JHIS54
JGLU127

site_idAD5
Number of Residues9
Detailsbinding site for residue HEM K 301
ChainResidue
JLEU19
JMET52
JGLU56
KASN23
KPHE26
KPHE49
KMET52
KARG53
KGLU56

site_idAD6
Number of Residues4
Detailsbinding site for residue FE2 K 302
ChainResidue
KGLU18
KGLU51
KHIS54
KGLU127

site_idAD7
Number of Residues4
Detailsbinding site for residue FE2 L 201
ChainResidue
LGLU18
LGLU51
LHIS54
LGLU127

site_idAD8
Number of Residues7
Detailsbinding site for residue HEM L 202
ChainResidue
LPHE26
LMET52
LARG53
LGLU56
LTYR71
MPHE26
MMET52

site_idAD9
Number of Residues4
Detailsbinding site for residue FE2 M 201
ChainResidue
MGLU18
MGLU51
MHIS54
MGLU127

site_idAE1
Number of Residues8
Detailsbinding site for residue HEM N 201
ChainResidue
NPHE26
NARG45
NMET52
NGLU56
HMET52
HARG53
HALA55
HGLU56

site_idAE2
Number of Residues4
Detailsbinding site for residue FE2 N 202
ChainResidue
NGLU18
NGLU51
NHIS54
NGLU127

site_idAE3
Number of Residues4
Detailsbinding site for residue FE2 O 201
ChainResidue
OGLU18
OGLU51
OHIS54
OGLU127

site_idAE4
Number of Residues9
Detailsbinding site for residue HEM O 202
ChainResidue
OLEU19
OASN23
OPHE26
OPHE49
OMET52
OTYR71
PLEU19
PASN23
PMET52

site_idAE5
Number of Residues4
Detailsbinding site for residue FE2 P 200
ChainResidue
PGLU18
PGLU51
PHIS54
PGLU127

site_idAE6
Number of Residues3
Detailsbinding site for residue FE2 Q 201
ChainResidue
QGLU47
QGLU51
QHIS130

site_idAE7
Number of Residues7
Detailsbinding site for residue HEM Q 202
ChainResidue
QPHE26
QMET52
QGLU56
QTYR71
RPHE26
RARG45
RMET52

site_idAE8
Number of Residues4
Detailsbinding site for residue FE2 R 201
ChainResidue
RGLU18
RGLU51
RHIS54
RGLU127

site_idAE9
Number of Residues4
Detailsbinding site for residue FE2 S 201
ChainResidue
SGLU18
SGLU51
SHIS54
SGLU127

site_idAF1
Number of Residues11
Detailsbinding site for residue HEM S 202
ChainResidue
ILEU19
IPHE26
IMET52
IGLU56
SASN23
SPHE26
SARG45
SPHE49
SMET52
SGLU56
STYR71

site_idAF2
Number of Residues4
Detailsbinding site for residue FE2 T 201
ChainResidue
TGLU18
TGLU51
THIS54
TGLU127

site_idAF3
Number of Residues8
Detailsbinding site for residue HEM U 201
ChainResidue
TLEU19
TASN23
TMET52
TTYR71
UASN23
UPHE26
UMET52
UGLU56

site_idAF4
Number of Residues4
Detailsbinding site for residue FE2 U 202
ChainResidue
UGLU18
UGLU51
UHIS54
UGLU127

site_idAF5
Number of Residues4
Detailsbinding site for residue FE2 V 201
ChainResidue
VGLU18
VGLU51
VHIS54
VGLU127

site_idAF6
Number of Residues9
Detailsbinding site for residue HEM V 202
ChainResidue
VPHE26
VPHE49
VMET52
VGLU56
VTYR71
WLEU19
WPHE26
WARG45
WMET52

site_idAF7
Number of Residues4
Detailsbinding site for residue FE2 W 201
ChainResidue
WGLU18
WGLU51
WHIS54
WGLU127

site_idAF8
Number of Residues6
Detailsbinding site for residue HEM X 201
ChainResidue
GPHE26
GMET52
XASN23
XPHE26
XMET52
XTYR71

site_idAF9
Number of Residues4
Detailsbinding site for residue FE2 X 202
ChainResidue
XGLU18
XGLU51
XHIS54
XGLU127

Functional Information from PROSITE/UniProt
site_idPS00549
Number of Residues19
DetailsBACTERIOFERRITIN Bacterioferritin signature. MqGdpeVIefLneqLtaeL
ChainResidueDetails
AMET1-LEU19

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues144
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00085
ChainResidueDetails
AGLU18
BGLU94
QGLU94
QGLU127
QHIS130
RGLU18
RGLU51
RHIS54
RGLU94
RGLU127
RHIS130
SGLU18
BGLU127
SGLU51
SHIS54
SGLU94
SGLU127
SHIS130
TGLU18
TGLU51
THIS54
TGLU94
TGLU127
BHIS130
THIS130
UGLU18
UGLU51
UHIS54
UGLU94
UGLU127
UHIS130
VGLU18
VGLU51
VHIS54
CGLU18
VGLU94
VGLU127
VHIS130
WGLU18
WGLU51
WHIS54
WGLU94
WGLU127
WHIS130
XGLU18
CGLU51
XGLU51
XHIS54
XGLU94
XGLU127
XHIS130
CHIS54
CGLU94
CGLU127
CHIS130
DGLU18
AGLU51
DGLU51
DHIS54
DGLU94
DGLU127
DHIS130
FGLU18
FGLU51
FHIS54
FGLU94
FGLU127
AHIS54
FHIS130
EGLU18
EGLU51
EHIS54
EGLU94
EGLU127
EHIS130
GGLU18
GGLU51
GHIS54
AGLU94
GGLU94
GGLU127
GHIS130
HGLU18
HGLU51
HHIS54
HGLU94
HGLU127
HHIS130
IGLU18
AGLU127
IGLU51
IHIS54
IGLU94
IGLU127
IHIS130
JGLU18
JGLU51
JHIS54
JGLU94
JGLU127
AHIS130
JHIS130
KGLU18
KGLU51
KHIS54
KGLU94
KGLU127
KHIS130
LGLU18
LGLU51
LHIS54
BGLU18
LGLU94
LGLU127
LHIS130
MGLU18
MGLU51
MHIS54
MGLU94
MGLU127
MHIS130
NGLU18
BGLU51
NGLU51
NHIS54
NGLU94
NGLU127
NHIS130
OGLU18
OGLU51
OHIS54
OGLU94
OGLU127
BHIS54
OHIS130
PGLU18
PGLU51
PHIS54
PGLU94
PGLU127
PHIS130
QGLU18
QGLU51
QHIS54

site_idSWS_FT_FI2
Number of Residues24
DetailsBINDING: axial binding residue => ECO:0000255|PROSITE-ProRule:PRU00085
ChainResidueDetails
AMET52
JMET52
KMET52
LMET52
MMET52
NMET52
OMET52
PMET52
QMET52
RMET52
SMET52
BMET52
TMET52
UMET52
VMET52
WMET52
XMET52
CMET52
DMET52
FMET52
EMET52
GMET52
HMET52
IMET52

226707

PDB entries from 2024-10-30

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