6K3J
Solution structure of APOBEC3G-CD2 with ssDNA, Product A
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue ZN A 401 |
| Chain | Residue |
| A | HIS257 |
| A | CYS288 |
| A | CYS291 |
Functional Information from PROSITE/UniProt
| site_id | PS00903 |
| Number of Residues | 39 |
| Details | CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAElcFLdvipfwkldldqdyrvtcftsws..........PCfs......CaqeM |
| Chain | Residue | Details |
| A | HIS257-MET295 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU01083, ECO:0000269|PubMed:18288108, ECO:0000269|PubMed:18849968, ECO:0000269|PubMed:19153609, ECO:0000269|PubMed:25542899, ECO:0000269|PubMed:36754086, ECO:0007744|PDB:4ROV, ECO:0007744|PDB:4ROW, ECO:0007744|PDB:8CX0, ECO:0007744|PDB:8CX1 |
| Chain | Residue | Details |
| A | GLU259 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:18288108, ECO:0000269|PubMed:18849968, ECO:0000269|PubMed:19153609, ECO:0000269|PubMed:25542899, ECO:0000269|PubMed:36754086, ECO:0000269|PubMed:37419875, ECO:0007744|PDB:4ROV, ECO:0007744|PDB:4ROW, ECO:0007744|PDB:8CX0, ECO:0007744|PDB:8CX1, ECO:0007744|PDB:8H0I, ECO:0007744|PDB:8J62 |
| Chain | Residue | Details |
| A | HIS257 | |
| A | CYS288 | |
| A | CYS291 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Interaction with DNA => ECO:0000305 |
| Chain | Residue | Details |
| A | ASN244 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by PKA and CAMK2 => ECO:0000269|PubMed:21659520 |
| Chain | Residue | Details |
| A | THR218 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CROSSLNK: (Microbial infection) Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:23318957, ECO:0000305|PubMed:31253590 |
| Chain | Residue | Details |
| A | LYS249 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | CROSSLNK: (Microbial infection) Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:19887642, ECO:0000305|PubMed:23318957, ECO:0000305|PubMed:31253590 |
| Chain | Residue | Details |
| A | LYS297 | |
| A | LYS303 | |
| A | LYS334 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CROSSLNK: (Microbial infection) Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:23318957 |
| Chain | Residue | Details |
| A | LYS270 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | CROSSLNK: (Microbial infection) Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:19887642 |
| Chain | Residue | Details |
| A | LYS301 |
