6K28
Crystal structure of the 5-(Hydroxyethyl)-methylthiazole Kinase ThiM from Klebsiella pneumonia in complex with TZE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004417 | molecular_function | hydroxyethylthiazole kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0009228 | biological_process | thiamine biosynthetic process |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004417 | molecular_function | hydroxyethylthiazole kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0009228 | biological_process | thiamine biosynthetic process |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004417 | molecular_function | hydroxyethylthiazole kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0009228 | biological_process | thiamine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue TZE A 301 |
| Chain | Residue |
| A | PRO47 |
| A | MET49 |
| B | ASN29 |
| B | GLY71 |
| B | VAL196 |
| B | CYS200 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue TZE A 302 |
| Chain | Residue |
| C | PRO47 |
| C | MET49 |
| A | ASN29 |
| A | GLY71 |
| A | CYS200 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 303 |
| Chain | Residue |
| A | ASP98 |
| A | ARG124 |
| A | GLU129 |
| A | HOH539 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 301 |
| Chain | Residue |
| B | ASP98 |
| B | ARG124 |
| B | GLU129 |
| B | HOH410 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue TZE C 301 |
| Chain | Residue |
| B | PRO47 |
| B | MET49 |
| C | GLY71 |
| C | VAL196 |
| C | GLY197 |
| C | CYS200 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 302 |
| Chain | Residue |
| C | ASP98 |
| C | VAL100 |
| C | ARG124 |
| C | GLU129 |
| C | HOH462 |
