6K1H

Structure of membrane protein

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005886	cellular_component	plasma membrane
B	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
B	0015761	biological_process	mannose transmembrane transport
B	0015764	biological_process	N-acetylglucosamine transport
B	0016020	cellular_component	membrane
B	0022870	molecular_function	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
B	0098708	biological_process	glucose import across plasma membrane
B	1902495	cellular_component	transmembrane transporter complex
B	1990539	biological_process	fructose import across plasma membrane
C	0005886	cellular_component	plasma membrane
C	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
C	0015761	biological_process	mannose transmembrane transport
C	0015764	biological_process	N-acetylglucosamine transport
C	0016020	cellular_component	membrane
C	0022870	molecular_function	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
C	0098708	biological_process	glucose import across plasma membrane
C	1902495	cellular_component	transmembrane transporter complex
C	1990539	biological_process	fructose import across plasma membrane
E	0005886	cellular_component	plasma membrane
E	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
E	0015761	biological_process	mannose transmembrane transport
E	0015764	biological_process	N-acetylglucosamine transport
E	0016020	cellular_component	membrane
E	0022870	molecular_function	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
E	0098708	biological_process	glucose import across plasma membrane
E	1902495	cellular_component	transmembrane transporter complex
E	1990539	biological_process	fructose import across plasma membrane
F	0005886	cellular_component	plasma membrane
F	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
F	0015761	biological_process	mannose transmembrane transport
F	0015764	biological_process	N-acetylglucosamine transport
F	0016020	cellular_component	membrane
F	0022870	molecular_function	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
F	0098708	biological_process	glucose import across plasma membrane
F	1902495	cellular_component	transmembrane transporter complex
F	1990539	biological_process	fructose import across plasma membrane
Y	0005886	cellular_component	plasma membrane
Y	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
Y	0015761	biological_process	mannose transmembrane transport
Y	0015764	biological_process	N-acetylglucosamine transport
Y	0016020	cellular_component	membrane
Y	0022870	molecular_function	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
Y	0098708	biological_process	glucose import across plasma membrane
Y	1902495	cellular_component	transmembrane transporter complex
Y	1990539	biological_process	fructose import across plasma membrane
Z	0005886	cellular_component	plasma membrane
Z	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
Z	0015761	biological_process	mannose transmembrane transport
Z	0015764	biological_process	N-acetylglucosamine transport
Z	0016020	cellular_component	membrane
Z	0022870	molecular_function	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
Z	0098708	biological_process	glucose import across plasma membrane
Z	1902495	cellular_component	transmembrane transporter complex
Z	1990539	biological_process	fructose import across plasma membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue MAN Z 301

Chain	Residue
Y	ASN65
Z	TRP127
Y	GLY67
Z	GLN32
Z	TRP35
Z	GLN41
Z	ASN76
Z	THR77
Z	GLN78
Z	ASP123

---

site_id	AC2
Number of Residues	10
Details	binding site for residue MAN F 301

Chain	Residue
E	ASN65
E	GLY67
F	GLN32
F	TRP35
F	GLN41
F	ASN76
F	THR77
F	GLN78
F	ASP123
F	TRP127

---

site_id	AC3
Number of Residues	10
Details	binding site for residue MAN C 301

Chain	Residue
B	ASN65
B	GLY67
C	GLN32
C	TRP35
C	GLN41
C	ASN76
C	THR77
C	GLN78
C	ASP123
C	TRP127

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	39
Details	TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:31209249, ECO:0000305|PubMed:32710850, ECO:0000305|PubMed:7811395

Chain	Residue	Details
Z	MET4-THR17
F	MET4-THR17
C	MET4-THR17

---

site_id	SWS_FT_FI2
Number of Residues	207
Details	INTRAMEM: INTRAMEM => ECO:0000305|PubMed:32710850

Chain	Residue	Details
Z	GLN18-ARG55
Z	ALA63-GLN95
F	GLN18-ARG55
F	ALA63-GLN95
C	GLN18-ARG55
C	ALA63-GLN95

---

site_id	SWS_FT_FI3
Number of Residues	81
Details	TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:32710850

Chain	Residue	Details
Z	LEU56-GLU62
C	ARG96-ASP103
C	ILE177-GLY186
C	ARG259-PRO264
Z	ARG96-ASP103
Z	ILE177-GLY186
Z	ARG259-PRO264
F	LEU56-GLU62
F	ARG96-ASP103
F	ILE177-GLY186
F	ARG259-PRO264
C	LEU56-GLU62

---

site_id	SWS_FT_FI4
Number of Residues	369
Details	TRANSMEM: TRANSMEM => ECO:0000305|PubMed:32710850

Chain	Residue	Details
Z	ASP104-MET143
F	LEU265-LEU283
C	ASP104-MET143
C	LEU148-GLY176
C	PHE187-HIS212
C	LEU245-LEU258
C	LEU265-LEU283
Z	LEU148-GLY176
Z	PHE187-HIS212
Z	LEU245-LEU258
Z	LEU265-LEU283
F	ASP104-MET143
F	LEU148-GLY176
F	PHE187-HIS212
F	LEU245-LEU258

---

site_id	SWS_FT_FI5
Number of Residues	102
Details	TOPO_DOM: Periplasmic => ECO:0000305|PubMed:32710850

Chain	Residue	Details
Z	SER144-LEU147
Z	VAL213-GLY244
F	SER144-LEU147
F	VAL213-GLY244
C	SER144-LEU147
C	VAL213-GLY244

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	TOPO_DOM: Periplasmic => ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:31209249, ECO:0000269|PubMed:8774730, ECO:0000305|PubMed:32710850

Chain	Residue	Details
Z	LEU284-LEU286
F	LEU284-LEU286
C	LEU284-LEU286

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	MOD_RES: N-formylmethionine => ECO:0000305|PubMed:2951378

Chain	Residue	Details
Z	MET4
F	MET4
C	MET4

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