6K13
Crystal Structure Basis for BmLDH Complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004459 | molecular_function | L-lactate dehydrogenase (NAD+) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006089 | biological_process | lactate metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004459 | molecular_function | L-lactate dehydrogenase (NAD+) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006089 | biological_process | lactate metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue OXM A 401 |
| Chain | Residue |
| A | GLN100 |
| A | ARG106 |
| A | ASN138 |
| A | ARG169 |
| A | HIS193 |
| A | ALA238 |
| A | THR248 |
| A | NAD402 |
| site_id | AC2 |
| Number of Residues | 28 |
| Details | binding site for residue NAD A 402 |
| Chain | Residue |
| A | ALA30 |
| A | VAL31 |
| A | ASP52 |
| A | VAL53 |
| A | VAL54 |
| A | LYS57 |
| A | THR95 |
| A | ALA96 |
| A | GLY97 |
| A | ALA98 |
| A | ARG99 |
| A | ILE116 |
| A | ILE120 |
| A | VAL136 |
| A | ASN138 |
| A | SER161 |
| A | HIS193 |
| A | THR248 |
| A | ILE252 |
| A | OXM401 |
| A | HOH508 |
| A | HOH512 |
| A | HOH517 |
| A | HOH524 |
| A | HOH531 |
| A | HOH535 |
| A | HOH554 |
| A | GLY29 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue OXM B 401 |
| Chain | Residue |
| B | GLN100 |
| B | ARG106 |
| B | ASN138 |
| B | ARG169 |
| B | HIS193 |
| B | ALA238 |
| B | THR248 |
| B | NAD402 |
| site_id | AC4 |
| Number of Residues | 26 |
| Details | binding site for residue NAD B 402 |
| Chain | Residue |
| B | GLY29 |
| B | ALA30 |
| B | VAL31 |
| B | ASP52 |
| B | VAL53 |
| B | THR95 |
| B | ALA96 |
| B | GLY97 |
| B | ALA98 |
| B | ARG99 |
| B | ILE120 |
| B | VAL136 |
| B | ASN138 |
| B | SER161 |
| B | LEU165 |
| B | HIS193 |
| B | THR248 |
| B | ILE252 |
| B | OXM401 |
| B | HOH510 |
| B | HOH519 |
| B | HOH521 |
| B | HOH526 |
| B | HOH534 |
| B | HOH543 |
| B | HOH550 |
Functional Information from PROSITE/UniProt
| site_id | PS00064 |
| Number of Residues | 7 |
| Details | L_LDH L-lactate dehydrogenase active site. LGEHGDS |
| Chain | Residue | Details |
| A | LEU190-SER196 |
