6JTB
Crystal structure of dipeptidyl peptidase 11 (DPP11) with citrate from Porphyromonas gingivalis (Space)
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue PEG A 801 |
| Chain | Residue |
| A | TRP219 |
| A | THR651 |
| A | GLY652 |
| A | ARG673 |
| A | CIT802 |
| A | CIT804 |
| A | K810 |
| A | HOH1057 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue CIT A 802 |
| Chain | Residue |
| A | TRP219 |
| A | THR651 |
| A | GLY652 |
| A | SER655 |
| A | PHE671 |
| A | ASP672 |
| A | ARG673 |
| A | PEG801 |
| A | K809 |
| A | HOH967 |
| A | HOH987 |
| A | HOH1038 |
| A | HOH1147 |
| A | HOH1305 |
| A | HOH1342 |
| A | HOH1360 |
| A | HIS85 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue CIT A 803 |
| Chain | Residue |
| A | ARG536 |
| A | LYS537 |
| A | ASN540 |
| A | ARG632 |
| A | GOL807 |
| A | HOH919 |
| A | HOH963 |
| A | HOH974 |
| A | HOH1039 |
| A | HOH1121 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue CIT A 804 |
| Chain | Residue |
| A | THR278 |
| A | HIS280 |
| A | ARG299 |
| A | ARG337 |
| A | PEG801 |
| A | K810 |
| A | HOH910 |
| A | HOH1179 |
| A | HOH1401 |
| A | HOH1433 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 805 |
| Chain | Residue |
| A | ASP60 |
| A | PHE124 |
| A | LYS194 |
| A | PRO253 |
| A | LYS254 |
| A | ARG255 |
| A | HOH1041 |
| A | HOH1169 |
| A | HOH1410 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 806 |
| Chain | Residue |
| A | ASP297 |
| A | ARG301 |
| A | MET396 |
| A | HOH935 |
| A | HOH1054 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 807 |
| Chain | Residue |
| A | LYS537 |
| A | ARG632 |
| A | ALA634 |
| A | ARG636 |
| A | CIT803 |
| A | HOH974 |
| A | HOH1039 |
| A | HOH1235 |
| A | HOH1257 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 808 |
| Chain | Residue |
| A | ASP546 |
| A | HOH1008 |
| A | HOH1232 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue K A 809 |
| Chain | Residue |
| A | ASN218 |
| A | TRP219 |
| A | ASP672 |
| A | CIT802 |
| A | HOH1057 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue K A 810 |
| Chain | Residue |
| A | THR278 |
| A | THR651 |
| A | ASP681 |
| A | PEG801 |
| A | CIT804 |
| A | HOH1287 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"V5YM14","evidenceCode":"ECO:0000250"},{"source":"PubMed","id":"26057589","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"V5YM14","evidenceCode":"ECO:0000250"},{"source":"PubMed","id":"21896480","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"26057589","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Is essential for the Asp/Glu P1 specificity of DPP11; involved in the recognition of the Asp/Glu residue at the P1 position of substrate peptides","evidences":[{"source":"PubMed","id":"26057589","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
