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6JSI

Co-purified Fatty Acid Synthase

Functional Information from GO Data
ChainGOidnamespacecontents
A0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
A0006633biological_processfatty acid biosynthetic process
A0016746molecular_functionacyltransferase activity
B0003824molecular_functioncatalytic activity
B0004312molecular_functionfatty acid synthase activity
B0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
B0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
B0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
B0004321molecular_functionfatty-acyl-CoA synthase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005811cellular_componentlipid droplet
B0005829cellular_componentcytosol
B0005835cellular_componentfatty acid synthase complex
B0006629biological_processlipid metabolic process
B0006631biological_processfatty acid metabolic process
B0006633biological_processfatty acid biosynthetic process
B0016297molecular_functionfatty acyl-[ACP] hydrolase activity
B0016409molecular_functionpalmitoyltransferase activity
B0016491molecular_functionoxidoreductase activity
B0016740molecular_functiontransferase activity
B0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
B0016787molecular_functionhydrolase activity
B0016829molecular_functionlyase activity
B0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
B0042759biological_processlong-chain fatty acid biosynthetic process
B0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
D0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
D0006633biological_processfatty acid biosynthetic process
D0016746molecular_functionacyltransferase activity
E0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
E0006633biological_processfatty acid biosynthetic process
E0016746molecular_functionacyltransferase activity
F0003824molecular_functioncatalytic activity
F0004312molecular_functionfatty acid synthase activity
F0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
F0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
F0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
F0004321molecular_functionfatty-acyl-CoA synthase activity
F0005515molecular_functionprotein binding
F0005737cellular_componentcytoplasm
F0005739cellular_componentmitochondrion
F0005811cellular_componentlipid droplet
F0005829cellular_componentcytosol
F0005835cellular_componentfatty acid synthase complex
F0006629biological_processlipid metabolic process
F0006631biological_processfatty acid metabolic process
F0006633biological_processfatty acid biosynthetic process
F0016297molecular_functionfatty acyl-[ACP] hydrolase activity
F0016409molecular_functionpalmitoyltransferase activity
F0016491molecular_functionoxidoreductase activity
F0016740molecular_functiontransferase activity
F0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
F0016787molecular_functionhydrolase activity
F0016829molecular_functionlyase activity
F0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
F0042759biological_processlong-chain fatty acid biosynthetic process
F0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
G0003824molecular_functioncatalytic activity
G0004312molecular_functionfatty acid synthase activity
G0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
G0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
G0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
G0004321molecular_functionfatty-acyl-CoA synthase activity
G0005515molecular_functionprotein binding
G0005737cellular_componentcytoplasm
G0005739cellular_componentmitochondrion
G0005811cellular_componentlipid droplet
G0005829cellular_componentcytosol
G0005835cellular_componentfatty acid synthase complex
G0006629biological_processlipid metabolic process
G0006631biological_processfatty acid metabolic process
G0006633biological_processfatty acid biosynthetic process
G0016297molecular_functionfatty acyl-[ACP] hydrolase activity
G0016409molecular_functionpalmitoyltransferase activity
G0016491molecular_functionoxidoreductase activity
G0016740molecular_functiontransferase activity
G0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
G0016787molecular_functionhydrolase activity
G0016829molecular_functionlyase activity
G0019171molecular_function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
G0042759biological_processlong-chain fatty acid biosynthetic process
G0141148molecular_functionenoyl-[acyl-carrier-protein] reductase (NADPH) activity
Functional Information from PROSITE/UniProt
site_idPS00606
Number of Residues17
DetailsKS3_1 Ketosynthase family 3 (KS3) active site signature. GPIktPVgACATSveSV
ChainResidueDetails
AGLY1296-VAL1312

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsActive site: {"description":"For acetyltransferase activity","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues3
DetailsModified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

240971

PDB entries from 2025-08-27

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