6JQQ

KatE H392C from Escherichia coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004096	molecular_function	catalase activity
A	0004601	molecular_function	peroxidase activity
A	0005829	cellular_component	cytosol
A	0006979	biological_process	response to oxidative stress
A	0020037	molecular_function	heme binding
A	0042744	biological_process	hydrogen peroxide catabolic process
A	0046872	molecular_function	metal ion binding
A	0098869	biological_process	cellular oxidant detoxification
B	0004096	molecular_function	catalase activity
B	0004601	molecular_function	peroxidase activity
B	0005829	cellular_component	cytosol
B	0006979	biological_process	response to oxidative stress
B	0020037	molecular_function	heme binding
B	0042744	biological_process	hydrogen peroxide catabolic process
B	0046872	molecular_function	metal ion binding
B	0098869	biological_process	cellular oxidant detoxification
C	0004096	molecular_function	catalase activity
C	0004601	molecular_function	peroxidase activity
C	0005829	cellular_component	cytosol
C	0006979	biological_process	response to oxidative stress
C	0020037	molecular_function	heme binding
C	0042744	biological_process	hydrogen peroxide catabolic process
C	0046872	molecular_function	metal ion binding
C	0098869	biological_process	cellular oxidant detoxification
D	0004096	molecular_function	catalase activity
D	0004601	molecular_function	peroxidase activity
D	0005829	cellular_component	cytosol
D	0006979	biological_process	response to oxidative stress
D	0020037	molecular_function	heme binding
D	0042744	biological_process	hydrogen peroxide catabolic process
D	0046872	molecular_function	metal ion binding
D	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue HEM A 801

Chain	Residue
A	ARG125
A	HIS275
A	PHE391
A	ARG411
A	SER414
A	TYR415
A	THR418
A	GLN419
A	ARG422
A	VAL127
A	HIS128
A	ARG165
A	VAL199
A	GLY200
A	ASN201
A	PHE206
A	PHE214

---

site_id	AC2
Number of Residues	19
Details	binding site for residue HEM B 801

Chain	Residue
B	ARG125
B	VAL127
B	HIS128
B	ARG165
B	GLY184
B	VAL199
B	GLY200
B	ASN201
B	PHE206
B	PHE214
B	ILE274
B	PHE391
B	ARG411
B	SER414
B	TYR415
B	THR418
B	GLN419
B	ARG422
B	HOH920

---

site_id	AC3
Number of Residues	15
Details	binding site for residue HEM C 801

Chain	Residue
C	ARG125
C	VAL127
C	HIS128
C	ARG165
C	VAL199
C	GLY200
C	ASN201
C	PHE214
C	PHE391
C	ARG411
C	SER414
C	TYR415
C	THR418
C	GLN419
C	ARG422

---

site_id	AC4
Number of Residues	5
Details	binding site for residue EDO C 802

Chain	Residue
B	GLU224
B	VAL535
C	GLN48
C	PRO49
C	THR50

---

site_id	AC5
Number of Residues	17
Details	binding site for residue HEM D 801

Chain	Residue
D	ARG125
D	VAL127
D	HIS128
D	ARG165
D	VAL199
D	GLY200
D	ASN201
D	PHE214
D	ILE274
D	HIS275
D	PHE391
D	ARG411
D	SER414
D	TYR415
D	THR418
D	GLN419
D	ARG422

---

Functional Information from PROSITE/UniProt

site_id	PS00437
Number of Residues	9
Details	CATALASE_1 Catalase proximal heme-ligand signature. RLFSYiDTQ

Chain	Residue	Details
A	ARG411-GLN419

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site_id	PS00438
Number of Residues	17
Details	CATALASE_2 Catalase proximal active site signature. FdHeripERivHarGSA

Chain	Residue	Details
A	PHE117-ALA133

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