6JNM
REF6 ZnF2-4-NAC004-mC3 complex
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1401 |
| Chain | Residue |
| A | CYS1268 |
| A | CYS1273 |
| A | HIS1286 |
| A | HIS1290 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1402 |
| Chain | Residue |
| A | CYS1298 |
| A | CYS1303 |
| A | HIS1316 |
| A | HIS1320 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1403 |
| Chain | Residue |
| A | CYS1333 |
| A | HIS1346 |
| A | HIS1352 |
| A | CYS1328 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1401 |
| Chain | Residue |
| B | CYS1268 |
| B | CYS1273 |
| B | HIS1286 |
| B | HIS1290 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1402 |
| Chain | Residue |
| B | CYS1298 |
| B | CYS1303 |
| B | HIS1316 |
| B | HIS1320 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1403 |
| Chain | Residue |
| B | CYS1328 |
| B | CYS1333 |
| B | HIS1346 |
| B | HIS1352 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | binding site for Di-nucleotide DT F 4 and 5CM F 5 |
| Chain | Residue |
| B | ARG1294 |
| B | PHE1307 |
| B | SER1312 |
| B | GLU1315 |
| B | HIS1316 |
| B | PHE1339 |
| B | HOH1511 |
| B | HOH1525 |
| B | HOH1527 |
| E | DA7 |
| E | DG8 |
| E | DA9 |
| E | DG10 |
| F | DC3 |
| F | DT6 |
| F | HOH104 |
| F | HOH107 |
| F | HOH110 |
| F | HOH117 |
| F | HOH119 |
| site_id | AC8 |
| Number of Residues | 23 |
| Details | binding site for Di-nucleotide 5CM F 5 and DT F 6 |
| Chain | Residue |
| B | TYR1282 |
| B | VAL1289 |
| B | ARG1294 |
| B | PHE1307 |
| B | TRP1309 |
| B | TRP1311 |
| B | SER1312 |
| B | GLU1315 |
| B | HOH1516 |
| B | HOH1527 |
| E | DC6 |
| E | DA7 |
| E | DG8 |
| E | DA9 |
| F | DT4 |
| F | DG7 |
| F | HOH101 |
| F | HOH106 |
| F | HOH107 |
| F | HOH110 |
| F | HOH114 |
| F | HOH117 |
| F | HOH119 |
Functional Information from PROSITE/UniProt
| site_id | PS00028 |
| Number of Residues | 23 |
| Details | ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. CpikgCgknFfshkylvqHqrv..H |
| Chain | Residue | Details |
| A | CYS1268-HIS1290 | |
| A | CYS1298-HIS1320 | |
| A | CYS1328-HIS1352 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 48 |
| Details | ZN_FING: C2H2-type 2 => ECO:0000255|PROSITE-ProRule:PRU00042 |
| Chain | Residue | Details |
| A | ASN1266-HIS1290 | |
| B | ASN1266-HIS1290 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 48 |
| Details | ZN_FING: C2H2-type 3 => ECO:0000255|PROSITE-ProRule:PRU00042 |
| Chain | Residue | Details |
| A | LEU1296-HIS1320 | |
| B | LEU1296-HIS1320 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 52 |
| Details | ZN_FING: C2H2-type 4 => ECO:0000255|PROSITE-ProRule:PRU00042 |
| Chain | Residue | Details |
| A | TYR1326-HIS1352 | |
| B | TYR1326-HIS1352 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:32257379, ECO:0007744|PDB:6A57, ECO:0007744|PDB:6A58, ECO:0007744|PDB:6A59 |
| Chain | Residue | Details |
| A | HIS1263 | |
| A | HIS1280 | |
| B | HIS1263 | |
| B | HIS1280 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31048693, ECO:0000269|PubMed:32257379, ECO:0007744|PDB:6A57, ECO:0007744|PDB:6A58, ECO:0007744|PDB:6A59, ECO:0007744|PDB:6JNL, ECO:0007744|PDB:6JNN |
| Chain | Residue | Details |
| A | CYS1268 | |
| B | CYS1273 | |
| B | HIS1286 | |
| B | HIS1290 | |
| B | CYS1298 | |
| B | CYS1303 | |
| B | HIS1316 | |
| B | HIS1320 | |
| A | CYS1273 | |
| A | HIS1286 | |
| A | HIS1290 | |
| A | CYS1298 | |
| A | CYS1303 | |
| A | HIS1316 | |
| A | HIS1320 | |
| B | CYS1268 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31048693, ECO:0000269|PubMed:32257379, ECO:0007744|PDB:6A57, ECO:0007744|PDB:6A58, ECO:0007744|PDB:6A59, ECO:0007744|PDB:6JNL, ECO:0007744|PDB:6JNM, ECO:0007744|PDB:6JNN |
| Chain | Residue | Details |
| A | CYS1328 | |
| A | CYS1333 | |
| A | HIS1346 | |
| A | HIS1352 | |
| B | CYS1328 | |
| B | CYS1333 | |
| B | HIS1346 | |
| B | HIS1352 |
