6JNL

REF6 ZnF2-4-NAC004 complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 1401

Chain	Residue
A	CYS1268
A	CYS1273
A	HIS1286
A	HIS1290

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 1402

Chain	Residue
A	CYS1328
A	CYS1333
A	HIS1346
A	HIS1352

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 1403

Chain	Residue
A	CYS1303
A	HIS1316
A	HIS1320
A	CYS1298

---

site_id	AC4
Number of Residues	3
Details	binding site for residue MG A 1404

Chain	Residue
A	CYS1298
A	TRP1300
A	CYS1303

---

site_id	AC5
Number of Residues	5
Details	binding site for residue GOL D 101

Chain	Residue
C	DG10
C	DA11
D	DT4
D	DC5
D	HOH201

---

site_id	AC6
Number of Residues	6
Details	binding site for residue D5M C 101

Chain	Residue
A	PRO1299
A	TRP1300
A	LYS1301
C	DA11
D	DT1
D	DT2

---

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. CpikgCgknFfshkylvqHqrv..H

Chain	Residue	Details
A	CYS1268-HIS1290
A	CYS1298-HIS1320
A	CYS1328-HIS1352

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Zinc finger: {"description":"C2H2-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Zinc finger: {"description":"C2H2-type 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	26
Details	Zinc finger: {"description":"C2H2-type 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	73
Details	Region: {"description":"DNA-binding","evidences":[{"source":"PubMed","id":"31048693","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32257379","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6A57","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6JNL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6JNM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6JNN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31048693","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32257379","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6A57","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6A58","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6A59","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6JNL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6JNN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"32257379","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6A57","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6A58","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6A59","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31048693","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32257379","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6A57","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6A58","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6A59","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6JNL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6JNM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6JNN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---