6JLH

Structure of SCGN in complex with a Snap25 peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0007420	biological_process	brain development
A	0021522	biological_process	spinal cord motor neuron differentiation
A	0030425	cellular_component	dendrite
A	0043195	cellular_component	terminal bouton
A	0045202	cellular_component	synapse
A	0046872	molecular_function	metal ion binding
C	0005509	molecular_function	calcium ion binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0007420	biological_process	brain development
C	0021522	biological_process	spinal cord motor neuron differentiation
C	0030425	cellular_component	dendrite
C	0043195	cellular_component	terminal bouton
C	0045202	cellular_component	synapse
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CA A 301

Chain	Residue
A	ASP67
A	THR69
A	ASP71
A	ARG73
A	GLU78
A	HOH415

---

site_id	AC2
Number of Residues	6
Details	binding site for residue CA A 302

Chain	Residue
A	TYR120
A	GLU125
A	HOH420
A	ASP114
A	ASP116
A	SER118

---

site_id	AC3
Number of Residues	6
Details	binding site for residue CA A 303

Chain	Residue
A	ASP250
A	ASN252
A	ASP254
A	LYS256
A	GLN258
A	GLU261

---

site_id	AC4
Number of Residues	6
Details	binding site for residue CA A 304

Chain	Residue
A	ASP21
A	ASP23
A	ASN25
A	TYR27
A	GLU32
A	HOH432

---

site_id	AC5
Number of Residues	6
Details	binding site for residue CA A 305

Chain	Residue
A	ASP158
A	ASN160
A	ASP162
A	ARG164
A	HOH406
A	HOH438

---

site_id	AC6
Number of Residues	6
Details	binding site for residue CA A 306

Chain	Residue
A	ASP206
A	SER208
A	THR210
A	ALA212
A	GLU214
A	GLU217

---

site_id	AC7
Number of Residues	1
Details	binding site for residue CL A 307

Chain	Residue
A	GLN18

---

site_id	AC8
Number of Residues	6
Details	binding site for residue CA C 301

Chain	Residue
C	ASP67
C	THR69
C	ASP71
C	ARG73
C	GLU78
C	HOH412

---

site_id	AC9
Number of Residues	6
Details	binding site for residue CA C 302

Chain	Residue
C	ASP21
C	ASP23
C	ASN25
C	TYR27
C	GLU32
C	HOH419

---

site_id	AD1
Number of Residues	6
Details	binding site for residue CA C 303

Chain	Residue
C	ASP158
C	ASN160
C	ASP162
C	ARG164
C	HOH411
C	HOH448

---

site_id	AD2
Number of Residues	6
Details	binding site for residue CA C 304

Chain	Residue
C	ASP114
C	ASP116
C	SER118
C	TYR120
C	GLU125
C	HOH451

---

site_id	AD3
Number of Residues	6
Details	binding site for residue CA C 305

Chain	Residue
C	ASP250
C	ASN252
C	ASP254
C	LYS256
C	GLN258
C	GLU261

---

site_id	AD4
Number of Residues	6
Details	binding site for residue CA C 306

Chain	Residue
C	ASP206
C	SER208
C	THR210
C	ALA212
C	GLU214
C	GLU217

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DADDNGYIEgkEL

Chain	Residue	Details
A	ASP21-LEU33
A	ASP114-LEU126
A	ASP158-LEU170
A	ASP206-VAL218
A	ASP250-LEU262

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P60879

Chain	Residue	Details
B	SER1
A	GLU125
A	ASP158
A	ASN160
A	ASP162
A	ARG164
A	ASP169
A	ASP206
A	SER208
A	THR210
A	GLU217
D	SER1
A	ASP250
A	ASN252
A	ASP254
A	LYS256
A	GLU261
C	ASP21
C	ASP23
C	ASN25
C	TYR27
C	GLU32
A	ASN25
C	ASP114
C	ASP116
C	SER118
C	TYR120
C	GLU125
C	ASP158
C	ASN160
C	ASP162
C	ARG164
C	ASP169
A	TYR27
C	ASP206
C	SER208
C	THR210
C	GLU217
C	ASP250
C	ASN252
C	ASP254
C	LYS256
C	GLU261
A	GLU32
A	ASP114
A	ASP116
A	SER118
A	TYR120

---