6JL6

Crystal structure of aspartate transcarbamoylase from Trypanosoma cruzi in complex with phosphate (Pi).

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004070	molecular_function	aspartate carbamoyltransferase activity
A	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
A	0006520	biological_process	amino acid metabolic process
A	0016597	molecular_function	amino acid binding
A	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
A	0044205	biological_process	'de novo' UMP biosynthetic process
B	0004070	molecular_function	aspartate carbamoyltransferase activity
B	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
B	0006520	biological_process	amino acid metabolic process
B	0016597	molecular_function	amino acid binding
B	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
B	0044205	biological_process	'de novo' UMP biosynthetic process
C	0004070	molecular_function	aspartate carbamoyltransferase activity
C	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
C	0006520	biological_process	amino acid metabolic process
C	0016597	molecular_function	amino acid binding
C	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
C	0044205	biological_process	'de novo' UMP biosynthetic process
D	0004070	molecular_function	aspartate carbamoyltransferase activity
D	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
D	0006520	biological_process	amino acid metabolic process
D	0016597	molecular_function	amino acid binding
D	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
D	0044205	biological_process	'de novo' UMP biosynthetic process
E	0004070	molecular_function	aspartate carbamoyltransferase activity
E	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
E	0006520	biological_process	amino acid metabolic process
E	0016597	molecular_function	amino acid binding
E	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
E	0044205	biological_process	'de novo' UMP biosynthetic process
F	0004070	molecular_function	aspartate carbamoyltransferase activity
F	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
F	0006520	biological_process	amino acid metabolic process
F	0016597	molecular_function	amino acid binding
F	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
F	0044205	biological_process	'de novo' UMP biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue ASP C 501

Chain	Residue
C	ARG113
C	HOH659
C	HIS141
C	ARG174
C	ARG242
C	GLN244
C	LEU288
C	HOH615
C	HOH619
C	HOH643

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site_id	AC2
Number of Residues	6
Details	binding site for residue PO4 E 601

Chain	Residue
E	SER62
E	SER63
E	ARG64
E	THR65
E	ARG113
E	LEU288

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