6JIZ
Apo structure of an imine reductase at 1.76 Angstrom resolution
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0003858 | molecular_function | 3-hydroxybutyrate dehydrogenase activity |
A | 0005829 | cellular_component | cytosol |
A | 0016054 | biological_process | organic acid catabolic process |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0035064 | molecular_function | methylated histone binding |
A | 0050661 | molecular_function | NADP binding |
B | 0000166 | molecular_function | nucleotide binding |
B | 0003858 | molecular_function | 3-hydroxybutyrate dehydrogenase activity |
B | 0005829 | cellular_component | cytosol |
B | 0016054 | biological_process | organic acid catabolic process |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0035064 | molecular_function | methylated histone binding |
B | 0050661 | molecular_function | NADP binding |
C | 0000166 | molecular_function | nucleotide binding |
C | 0003858 | molecular_function | 3-hydroxybutyrate dehydrogenase activity |
C | 0005829 | cellular_component | cytosol |
C | 0016054 | biological_process | organic acid catabolic process |
C | 0016491 | molecular_function | oxidoreductase activity |
C | 0035064 | molecular_function | methylated histone binding |
C | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue ACT A 301 |
Chain | Residue |
A | GLN73 |
A | NH4305 |
A | HOH413 |
A | HOH486 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue ACT A 302 |
Chain | Residue |
A | GLN73 |
A | TYR76 |
A | HOH446 |
A | HOH627 |
site_id | AC3 |
Number of Residues | 3 |
Details | binding site for residue ACT A 303 |
Chain | Residue |
A | HOH450 |
B | HOH435 |
A | ARG158 |
site_id | AC4 |
Number of Residues | 1 |
Details | binding site for residue CL A 304 |
Chain | Residue |
A | TRP287 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue NH4 A 305 |
Chain | Residue |
A | ACT301 |
A | HOH417 |
A | HOH520 |
A | HOH533 |
site_id | AC6 |
Number of Residues | 3 |
Details | binding site for residue NA A 306 |
Chain | Residue |
A | THR70 |
A | HOH641 |
A | HOH659 |
site_id | AC7 |
Number of Residues | 6 |
Details | binding site for residue ACT B 301 |
Chain | Residue |
B | LEU231 |
B | GLY234 |
B | TYR291 |
B | GLU292 |
B | LYS295 |
C | GLU199 |
site_id | AC8 |
Number of Residues | 2 |
Details | binding site for residue ACT B 302 |
Chain | Residue |
B | HOH445 |
B | HOH489 |
site_id | AC9 |
Number of Residues | 3 |
Details | binding site for residue ACT B 303 |
Chain | Residue |
A | LYS111 |
B | ASN235 |
B | HOH524 |
site_id | AD1 |
Number of Residues | 1 |
Details | binding site for residue CL B 304 |
Chain | Residue |
B | ARG103 |
site_id | AD2 |
Number of Residues | 1 |
Details | binding site for residue CL B 305 |
Chain | Residue |
B | ARG229 |
site_id | AD3 |
Number of Residues | 6 |
Details | binding site for residue LW9 B 306 |
Chain | Residue |
B | LEU225 |
B | ALA241 |
B | MET245 |
B | MET246 |
B | HOH421 |
C | NAP302 |
site_id | AD4 |
Number of Residues | 4 |
Details | binding site for residue NA C 301 |
Chain | Residue |
B | LYS296 |
B | LYS297 |
B | HOH598 |
C | GLY261 |
site_id | AD5 |
Number of Residues | 38 |
Details | binding site for residue NAP C 302 |
Chain | Residue |
B | LEU240 |
B | MET245 |
B | THR249 |
B | LW9306 |
B | HOH421 |
C | GLY12 |
C | LEU13 |
C | GLY14 |
C | PRO15 |
C | MET16 |
C | ASN35 |
C | ARG36 |
C | THR37 |
C | ARG40 |
C | SER68 |
C | LEU69 |
C | THR70 |
C | ALA74 |
C | ASP77 |
C | ILE78 |
C | SER95 |
C | SER96 |
C | VAL121 |
C | THR123 |
C | PRO124 |
C | ALA125 |
C | TYR171 |
C | HOH424 |
C | HOH429 |
C | HOH441 |
C | HOH475 |
C | HOH494 |
C | HOH495 |
C | HOH502 |
C | HOH523 |
C | HOH534 |
C | HOH547 |
C | HOH559 |
site_id | AD6 |
Number of Residues | 4 |
Details | binding site for residue ACT C 303 |
Chain | Residue |
C | GLN73 |
C | HOH417 |
C | HOH444 |
C | HOH488 |
site_id | AD7 |
Number of Residues | 4 |
Details | binding site for residue CL C 304 |
Chain | Residue |
B | GLY261 |
C | LYS296 |
C | LYS297 |
C | HOH652 |
site_id | AD8 |
Number of Residues | 5 |
Details | binding site for residue CL C 305 |
Chain | Residue |
C | GLU83 |
C | TRP108 |
C | LYS111 |
C | HIS112 |
C | HOH655 |
site_id | AD9 |
Number of Residues | 3 |
Details | binding site for residue EDO C 306 |
Chain | Residue |
C | GLN18 |
C | ARG40 |
C | HOH528 |
site_id | AE1 |
Number of Residues | 2 |
Details | binding site for residue EDO C 307 |
Chain | Residue |
C | GLN73 |
C | TYR76 |