Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0016874 | molecular_function | ligase activity |
| A | 0016882 | molecular_function | cyclo-ligase activity |
| A | 0017000 | biological_process | antibiotic biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0016874 | molecular_function | ligase activity |
| B | 0016882 | molecular_function | cyclo-ligase activity |
| B | 0017000 | biological_process | antibiotic biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0016874 | molecular_function | ligase activity |
| C | 0016882 | molecular_function | cyclo-ligase activity |
| C | 0017000 | biological_process | antibiotic biosynthetic process |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0016874 | molecular_function | ligase activity |
| D | 0016882 | molecular_function | cyclo-ligase activity |
| D | 0017000 | biological_process | antibiotic biosynthetic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue TLA A 401 |
| Chain | Residue |
| A | TRP45 |
| A | PHE69 |
| A | ARG72 |
| A | VAL73 |
| A | HOH553 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue TLA A 402 |
| Chain | Residue |
| A | ARG254 |
| A | GLU269 |
| A | GLU271 |
| A | SER276 |
| A | ADP403 |
| A | MG404 |
| A | MG405 |
| A | HOH528 |
| A | HOH584 |
| A | CYS142 |
| A | TYR143 |
| A | LYS202 |
| A | ARG220 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | binding site for residue ADP A 403 |
| Chain | Residue |
| A | LYS92 |
| A | LYS137 |
| A | CYS142 |
| A | TYR143 |
| A | SER144 |
| A | GLN175 |
| A | PRO176 |
| A | TYR177 |
| A | VAL178 |
| A | GLU186 |
| A | MSE205 |
| A | LEU206 |
| A | LEU268 |
| A | GLU269 |
| A | TLA402 |
| A | MG404 |
| A | MG405 |
| A | HOH516 |
| A | HOH526 |
| A | HOH527 |
| A | HOH535 |
| A | HOH554 |
| A | HOH592 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 404 |
| Chain | Residue |
| A | LYS202 |
| A | GLU269 |
| A | TLA402 |
| A | ADP403 |
| A | HOH501 |
| A | HOH527 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 405 |
| Chain | Residue |
| A | GLU269 |
| A | GLU271 |
| A | TLA402 |
| A | ADP403 |
| A | HOH526 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue TLA B 401 |
| Chain | Residue |
| B | GLY114 |
| B | SER115 |
| B | ALA117 |
| B | ALA163 |
| B | LEU166 |
| B | ALA167 |
| B | HOH505 |
| B | HOH515 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue TLA B 402 |
| Chain | Residue |
| B | TRP45 |
| B | PHE69 |
| B | ARG72 |
| B | VAL73 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | binding site for residue TLA B 403 |
| Chain | Residue |
| B | CYS142 |
| B | TYR143 |
| B | LYS202 |
| B | ARG220 |
| B | ARG254 |
| B | GLU269 |
| B | GLU271 |
| B | SER276 |
| B | ADP404 |
| B | MG405 |
| B | MG406 |
| B | HOH512 |
| B | HOH538 |
| B | HOH570 |
| site_id | AC9 |
| Number of Residues | 25 |
| Details | binding site for residue ADP B 404 |
| Chain | Residue |
| B | HOH521 |
| B | HOH529 |
| B | HOH580 |
| B | HOH583 |
| B | LYS92 |
| B | VAL135 |
| B | LYS137 |
| B | GLY141 |
| B | CYS142 |
| B | TYR143 |
| B | SER144 |
| B | GLN175 |
| B | PRO176 |
| B | TYR177 |
| B | VAL178 |
| B | VAL181 |
| B | GLU186 |
| B | MSE205 |
| B | LEU206 |
| B | LEU268 |
| B | GLU269 |
| B | TLA403 |
| B | MG405 |
| B | MG406 |
| B | HOH512 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue MG B 405 |
| Chain | Residue |
| B | LYS202 |
| B | ASP256 |
| B | GLU269 |
| B | TLA403 |
| B | ADP404 |
| B | HOH504 |
| B | HOH512 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 406 |
| Chain | Residue |
| B | GLU269 |
| B | GLU271 |
| B | TLA403 |
| B | ADP404 |
| B | HOH521 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue TLA C 401 |
| Chain | Residue |
| C | GLY114 |
| C | SER115 |
| C | ALA117 |
| C | LEU166 |
| D | GLU227 |
| D | ASP228 |
| D | HOH558 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue TLA C 402 |
| Chain | Residue |
| C | TRP45 |
| C | PHE69 |
| C | ARG72 |
| C | VAL73 |
| C | VAL76 |
| C | HOH537 |
| site_id | AD5 |
| Number of Residues | 12 |
| Details | binding site for residue TLA C 403 |
| Chain | Residue |
| C | CYS142 |
| C | TYR143 |
| C | LYS202 |
| C | ARG220 |
| C | ARG254 |
| C | GLU269 |
| C | GLU271 |
| C | SER276 |
| C | ADP404 |
| C | MG405 |
| C | MG406 |
| C | HOH529 |
| site_id | AD6 |
| Number of Residues | 23 |
| Details | binding site for residue ADP C 404 |
| Chain | Residue |
| C | LYS92 |
| C | LYS137 |
| C | CYS142 |
| C | TYR143 |
| C | SER144 |
| C | GLN175 |
| C | PRO176 |
| C | TYR177 |
| C | VAL178 |
| C | VAL181 |
| C | GLU186 |
| C | MSE205 |
| C | LEU206 |
| C | LEU268 |
| C | GLU269 |
| C | TLA403 |
| C | MG405 |
| C | MG406 |
| C | HOH510 |
| C | HOH536 |
| C | HOH540 |
| C | HOH548 |
| C | HOH562 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue MG C 405 |
| Chain | Residue |
| C | LYS202 |
| C | GLU269 |
| C | TLA403 |
| C | ADP404 |
| C | HOH501 |
| C | HOH570 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 406 |
| Chain | Residue |
| C | GLU269 |
| C | GLU271 |
| C | TLA403 |
| C | ADP404 |
| C | HOH562 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue TLA D 401 |
| Chain | Residue |
| D | TRP45 |
| D | PHE69 |
| D | ARG72 |
| site_id | AE1 |
| Number of Residues | 14 |
| Details | binding site for residue TLA D 402 |
| Chain | Residue |
| D | TRP57 |
| D | CYS142 |
| D | TYR143 |
| D | LYS202 |
| D | PRO215 |
| D | ARG254 |
| D | GLU269 |
| D | GLU271 |
| D | SER276 |
| D | ADP403 |
| D | MG404 |
| D | MG405 |
| D | MG406 |
| D | HOH555 |
| site_id | AE2 |
| Number of Residues | 24 |
| Details | binding site for residue ADP D 403 |
| Chain | Residue |
| D | LYS92 |
| D | VAL135 |
| D | LYS137 |
| D | CYS142 |
| D | TYR143 |
| D | SER144 |
| D | GLN175 |
| D | PRO176 |
| D | TYR177 |
| D | VAL178 |
| D | VAL181 |
| D | GLU186 |
| D | MSE205 |
| D | LEU206 |
| D | LEU268 |
| D | GLU269 |
| D | TLA402 |
| D | MG404 |
| D | MG405 |
| D | HOH502 |
| D | HOH512 |
| D | HOH538 |
| D | HOH542 |
| D | HOH543 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue MG D 404 |
| Chain | Residue |
| D | LYS202 |
| D | ASP256 |
| D | GLU269 |
| D | TLA402 |
| D | ADP403 |
| D | HOH502 |
| D | HOH505 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue MG D 405 |
| Chain | Residue |
| D | GLY141 |
| D | CYS142 |
| D | GLU269 |
| D | GLU271 |
| D | TLA402 |
| D | ADP403 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue MG D 406 |
| Chain | Residue |
| D | TRP57 |
| D | GLU271 |
| D | GLU274 |
| D | TLA402 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"31793174","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31793174","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6JIL","evidenceCode":"ECO:0000312"}]} |
