Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | binding site for residue HEM A 501 |
| Chain | Residue |
| A | ASN242 |
| A | MET307 |
| A | HIS343 |
| A | ILE344 |
| A | ALA347 |
| A | ASN348 |
| A | ARG350 |
| A | ILE359 |
| A | ARG361 |
| A | LEU380 |
| A | PHE382 |
| A | LEU244 |
| A | VAL396 |
| A | GLN397 |
| A | LEU400 |
| A | OXY502 |
| A | HOH606 |
| A | HOH610 |
| A | HOH658 |
| A | PHE246 |
| A | ARG247 |
| A | GLY249 |
| A | SER250 |
| A | ALA251 |
| A | ILE288 |
| A | ASN290 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue OXY A 502 |
| Chain | Residue |
| A | ASP248 |
| A | ARG361 |
| A | HEM501 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue PEG A 503 |
| Chain | Residue |
| A | GLY224 |
| A | THR225 |
| A | ASN365 |
| A | TYR366 |
| A | SER367 |
| A | HOH703 |
| B | GLU223 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue PEG A 504 |
| Chain | Residue |
| A | ARG102 |
| A | HOH704 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue PEG A 505 |
| Chain | Residue |
| A | LYS221 |
| A | GLN222 |
| A | GLU223 |
| A | ASN368 |
| B | ASN368 |
| B | GLY369 |
| B | PGE516 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | ASP56 |
| A | ALA57 |
| A | PRO58 |
| A | HOH604 |
| B | PRO80 |
| B | ARG81 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | GLU99 |
| A | ARG102 |
| A | EDO508 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | ASN357 |
| A | ARG399 |
| A | EDO507 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 509 |
| Chain | Residue |
| A | ARG305 |
| A | ARG337 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 510 |
| Chain | Residue |
| A | PRO176 |
| A | EDO516 |
| B | THR235 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 511 |
| Chain | Residue |
| A | ASP181 |
| B | ASP61 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 512 |
| Chain | Residue |
| A | ARG350 |
| A | HOH681 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 513 |
| Chain | Residue |
| A | GLU302 |
| A | ASP341 |
| A | HOH700 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 515 |
| Chain | Residue |
| A | PRO274 |
| A | ALA275 |
| A | TRP276 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 516 |
| Chain | Residue |
| A | GLY51 |
| A | GLN53 |
| A | ASP56 |
| A | EDO510 |
| B | SER237 |
| site_id | AD7 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 518 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 519 |
| Chain | Residue |
| A | GLU101 |
| A | ASP436 |
| site_id | AD9 |
| Number of Residues | 23 |
| Details | binding site for residue HEM B 501 |
| Chain | Residue |
| B | OXY502 |
| B | HOH610 |
| B | HOH632 |
| B | HOH650 |
| B | ASN242 |
| B | PHE246 |
| B | ARG247 |
| B | GLY249 |
| B | SER250 |
| B | ALA251 |
| B | ILE288 |
| B | ASN290 |
| B | MET307 |
| B | HIS343 |
| B | ILE344 |
| B | ASN348 |
| B | ARG350 |
| B | ARG361 |
| B | PHE382 |
| B | PHE393 |
| B | VAL396 |
| B | GLN397 |
| B | ILE409 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue OXY B 502 |
| Chain | Residue |
| B | ASP248 |
| B | ARG361 |
| B | HEM501 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 503 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue PEG B 504 |
| Chain | Residue |
| B | ARG305 |
| B | THR336 |
| B | ARG337 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| B | GLU101 |
| B | LEU435 |
| B | ASP436 |
| site_id | AE5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 506 |
| Chain | Residue |
| B | LYS210 |
| B | ASN211 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 508 |
| Chain | Residue |
| A | VAL229 |
| A | GLU238 |
| A | ARG247 |
| B | LEU135 |
| B | GLY136 |
| B | PRO137 |
| site_id | AE7 |
| Number of Residues | 10 |
| Details | binding site for residue EDO B 509 |
| Chain | Residue |
| B | GLY151 |
| B | ASP152 |
| B | SER153 |
| B | HIS186 |
| B | GLY187 |
| B | TYR416 |
| B | PHE417 |
| B | HOH604 |
| B | HOH611 |
| B | HOH629 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 510 |
| Chain | Residue |
| A | GLY402 |
| A | GLU403 |
| A | PRO404 |
| B | GLY234 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 511 |
| Chain | Residue |
| B | PRO274 |
| B | ALA275 |
| B | TRP276 |
| B | ALA437 |
| site_id | AF1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 512 |
| Chain | Residue |
| B | ARG105 |
| B | THR106 |
| site_id | AF2 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 513 |
| site_id | AF3 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 514 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue PGE B 515 |
| Chain | Residue |
| B | GLU109 |
| B | ARG110 |
| B | GLN120 |
| B | THR130 |
| B | ASN211 |
| site_id | AF5 |
| Number of Residues | 6 |
| Details | binding site for residue PGE B 516 |
| Chain | Residue |
| A | TRP220 |
| A | LYS221 |
| A | PEG505 |
| B | VAL370 |
| B | THR371 |
| B | LYS372 |
| site_id | AF6 |
| Number of Residues | 8 |
| Details | binding site for residue PGE B 517 |
| Chain | Residue |
| A | ASN368 |
| B | LYS221 |
| B | GLN222 |
| B | GLU223 |
| B | ASN368 |
| B | GLU377 |
| B | ILE412 |
| B | HOH622 |
