6J9Q

Crystal structure of Trypanosoma brucei gambiense glycerol kinase complex with AMP-PNP.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004370	molecular_function	glycerol kinase activity
A	0005524	molecular_function	ATP binding
A	0005739	cellular_component	mitochondrion
A	0005975	biological_process	carbohydrate metabolic process
A	0006071	biological_process	glycerol metabolic process
A	0006072	biological_process	glycerol-3-phosphate metabolic process
A	0006641	biological_process	triglyceride metabolic process
A	0016301	molecular_function	kinase activity
A	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
A	0019563	biological_process	glycerol catabolic process
A	0046167	biological_process	glycerol-3-phosphate biosynthetic process
B	0004370	molecular_function	glycerol kinase activity
B	0005524	molecular_function	ATP binding
B	0005739	cellular_component	mitochondrion
B	0005975	biological_process	carbohydrate metabolic process
B	0006071	biological_process	glycerol metabolic process
B	0006072	biological_process	glycerol-3-phosphate metabolic process
B	0006641	biological_process	triglyceride metabolic process
B	0016301	molecular_function	kinase activity
B	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
B	0019563	biological_process	glycerol catabolic process
B	0046167	biological_process	glycerol-3-phosphate biosynthetic process
C	0004370	molecular_function	glycerol kinase activity
C	0005524	molecular_function	ATP binding
C	0005739	cellular_component	mitochondrion
C	0005975	biological_process	carbohydrate metabolic process
C	0006071	biological_process	glycerol metabolic process
C	0006072	biological_process	glycerol-3-phosphate metabolic process
C	0006641	biological_process	triglyceride metabolic process
C	0016301	molecular_function	kinase activity
C	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
C	0019563	biological_process	glycerol catabolic process
C	0046167	biological_process	glycerol-3-phosphate biosynthetic process
D	0004370	molecular_function	glycerol kinase activity
D	0005524	molecular_function	ATP binding
D	0005739	cellular_component	mitochondrion
D	0005975	biological_process	carbohydrate metabolic process
D	0006071	biological_process	glycerol metabolic process
D	0006072	biological_process	glycerol-3-phosphate metabolic process
D	0006641	biological_process	triglyceride metabolic process
D	0016301	molecular_function	kinase activity
D	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
D	0019563	biological_process	glycerol catabolic process
D	0046167	biological_process	glycerol-3-phosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue GOL A 601

Chain	Residue
A	ARG84
A	GLU85
A	TRP104
A	ASP254
A	GLN255

---

site_id	AC2
Number of Residues	9
Details	binding site for residue ANP A 602

Chain	Residue
A	ILE337
A	GLY421
A	GLY422
A	LEU423
A	LYS425
A	GLY275
A	THR276
A	GLY321
A	GLU325

---

site_id	AC3
Number of Residues	7
Details	binding site for residue GOL B 601

Chain	Residue
B	GLN83
B	ARG84
B	GLU85
B	TRP104
B	ASP254
B	GLN255
B	PHE279

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL B 602

Chain	Residue
B	THR11
B	THR12
B	SER13
B	THR276

---

site_id	AC5
Number of Residues	6
Details	binding site for residue ANP B 603

Chain	Residue
B	MET1
B	TYR3
B	ASP20
B	ARG22
B	ARG24
B	ASP69

---

site_id	AC6
Number of Residues	5
Details	binding site for residue GOL C 601

Chain	Residue
C	GLN83
C	ARG84
C	GLU85
C	ASP254
C	GLN255

---

site_id	AC7
Number of Residues	6
Details	binding site for residue ANP C 602

Chain	Residue
C	GLY275
C	THR276
C	GLY421
C	GLY422
C	LEU423
C	LYS425

---

site_id	AC8
Number of Residues	6
Details	binding site for residue GOL D 601

Chain	Residue
D	ARG84
D	GLU85
D	TRP104
D	ASP254
D	GLN255
D	GOL603

---

site_id	AC9
Number of Residues	6
Details	binding site for residue ANP D 602

Chain	Residue
D	TYR3
D	ASP20
D	ARG22
D	ARG24
D	VAL26
D	ASP69

---

site_id	AD1
Number of Residues	5
Details	binding site for residue GOL D 603

Chain	Residue
D	THR11
D	THR12
D	SER13
D	THR276
D	GOL601

---

Functional Information from PROSITE/UniProt

site_id	PS00445
Number of Residues	21
Details	FGGY_KINASES_2 FGGY family of carbohydrate kinases signature 2. GtIVGMtlkttra.HVIRAALQ

Chain	Residue	Details
A	GLY373-GLN393

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