6J90

Crystal Structure of GyraseB N-Terminal Domain complex with ATP from Salmonella Typhi at 2.2A Resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0006265	biological_process	DNA topological change

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue CL A 501

Chain	Residue
A	ASP6
A	SER7
A	THR80
A	GLY81

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site_id	AC2
Number of Residues	32
Details	binding site for residue ATP A 502

Chain	Residue
A	ASP73
A	ILE78
A	ILE94
A	ALA100
A	GLY101
A	GLY102
A	LYS103
A	TYR109
A	GLY114
A	LEU115
A	HIS116
A	GLY117
A	VAL118
A	GLY119
A	VAL120
A	THR165
A	LYS337
A	HOH602
A	HOH621
A	HOH653
A	HOH666
A	HOH686
A	HOH690
A	HOH716
A	HOH723
A	HOH739
A	HOH750
A	TYR5
A	ILE10
A	GLU42
A	ASN46
A	GLU50

---

site_id	AC3
Number of Residues	6
Details	binding site for residue GOL A 503

Chain	Residue
A	PHE41
A	ASP45
A	ARG190
A	PRO274
A	ARG276
A	HOH687

---

site_id	AC4
Number of Residues	9
Details	binding site for residue GOL A 504

Chain	Residue
A	GLY24
A	MET25
A	TYR26
A	GLY28
A	SER333
A	GLN335
A	THR336
A	HOH612
A	HOH776

---

site_id	AC5
Number of Residues	3
Details	binding site for residue PEG A 505

Chain	Residue
A	ARG20
A	HIS147
A	VAL149

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site_id	AC6
Number of Residues	4
Details	binding site for residue PEG A 506

Chain	Residue
A	PRO235
A	ILE236
A	PRO238
A	HOH857

---

site_id	AC7
Number of Residues	8
Details	binding site for residue PEG A 507

Chain	Residue
A	THR72
A	ASP73
A	VAL133
A	GLN135
A	LYS162
A	GLY164
A	THR165
A	HOH853

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