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6J7X

Complex of GGTaseIII, farnesyl-Ykt6, and GGPP

Functional Information from GO Data
ChainGOidnamespacecontents
A0008318molecular_functionprotein prenyltransferase activity
A0018342biological_processprotein prenylation
B0003824molecular_functioncatalytic activity
B0004659molecular_functionprenyltransferase activity
B0004661molecular_functionprotein geranylgeranyltransferase activity
B0004663molecular_functionRab geranylgeranyltransferase activity
B0005515molecular_functionprotein binding
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0005968cellular_componentRab-protein geranylgeranyltransferase complex
B0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
B0007601biological_processvisual perception
B0008270molecular_functionzinc ion binding
B0008318molecular_functionprotein prenyltransferase activity
B0018344biological_processprotein geranylgeranylation
B0031267molecular_functionsmall GTPase binding
B0036211biological_processprotein modification process
B0046872molecular_functionmetal ion binding
C0000139cellular_componentGolgi membrane
C0005484molecular_functionSNAP receptor activity
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005768cellular_componentendosome
C0005783cellular_componentendoplasmic reticulum
C0005794cellular_componentGolgi apparatus
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
C0006903biological_processvesicle targeting
C0006904biological_processvesicle docking involved in exocytosis
C0015031biological_processprotein transport
C0016020cellular_componentmembrane
C0016192biological_processvesicle-mediated transport
C0016740molecular_functiontransferase activity
C0019706molecular_functionprotein-cysteine S-palmitoyltransferase activity
C0030133cellular_componenttransport vesicle
C0030659cellular_componentcytoplasmic vesicle membrane
C0031201cellular_componentSNARE complex
C0031410cellular_componentcytoplasmic vesicle
C0033116cellular_componentendoplasmic reticulum-Golgi intermediate compartment membrane
C0042147biological_processretrograde transport, endosome to Golgi
C0043025cellular_componentneuronal cell body
C0045296molecular_functioncadherin binding
C0061025biological_processmembrane fusion
C0097440cellular_componentapical dendrite
C0097441cellular_componentbasal dendrite
Functional Information from PDB Data
site_idAC1
Number of Residues16
Detailsbinding site for residue GRG B 401
ChainResidue
ALYS135
BGLN193
BCYS196
BARG232
BLYS235
BTYR241
BTRP244
BPHE293
ATYR195
AASN196
BTYR51
BGLN103
BARG144
BPHE147
BHIS190
BGLY192

site_idAC2
Number of Residues3
Detailsbinding site for residue FMT B 402
ChainResidue
AGLU138
AILE141
BARG144

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
CSER159
BASP238
BCYS240
BTYR241
BHIS290

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Cysteine methyl ester => ECO:0000305
ChainResidueDetails
CCYS195

site_idSWS_FT_FI3
Number of Residues1
DetailsLIPID: S-palmitoyl cysteine => ECO:0000269|PubMed:15479160
ChainResidueDetails
CCYS194

site_idSWS_FT_FI4
Number of Residues1
DetailsLIPID: S-farnesyl cysteine => ECO:0000269|PubMed:15044687
ChainResidueDetails
CCYS195

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PDB entries from 2024-11-06

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