6J7F

Complex of GGTaseIII, farnesyl-Ykt6 (C-terminal methylated), and GGPP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008318	molecular_function	protein prenyltransferase activity
A	0018342	biological_process	protein prenylation
B	0003824	molecular_function	catalytic activity
B	0004659	molecular_function	prenyltransferase activity
B	0004661	molecular_function	protein geranylgeranyltransferase activity
B	0004663	molecular_function	Rab geranylgeranyltransferase activity
B	0005515	molecular_function	protein binding
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0005968	cellular_component	Rab-protein geranylgeranyltransferase complex
B	0007601	biological_process	visual perception
B	0008270	molecular_function	zinc ion binding
B	0008318	molecular_function	protein prenyltransferase activity
B	0018344	biological_process	protein geranylgeranylation
B	0031267	molecular_function	small GTPase binding
B	0036211	biological_process	protein modification process
B	0046872	molecular_function	metal ion binding
C	0000139	cellular_component	Golgi membrane
C	0005484	molecular_function	SNAP receptor activity
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005768	cellular_component	endosome
C	0005783	cellular_component	endoplasmic reticulum
C	0005794	cellular_component	Golgi apparatus
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
C	0006903	biological_process	vesicle targeting
C	0006904	biological_process	vesicle docking involved in exocytosis
C	0015031	biological_process	protein transport
C	0016020	cellular_component	membrane
C	0016192	biological_process	vesicle-mediated transport
C	0016740	molecular_function	transferase activity
C	0019706	molecular_function	protein-cysteine S-palmitoyltransferase activity
C	0030133	cellular_component	transport vesicle
C	0030659	cellular_component	cytoplasmic vesicle membrane
C	0031201	cellular_component	SNARE complex
C	0031410	cellular_component	cytoplasmic vesicle
C	0033116	cellular_component	endoplasmic reticulum-Golgi intermediate compartment membrane
C	0042147	biological_process	retrograde transport, endosome to Golgi
C	0043025	cellular_component	neuronal cell body
C	0045296	molecular_function	cadherin binding
C	0061025	biological_process	membrane fusion
C	0097440	cellular_component	apical dendrite
C	0097441	cellular_component	basal dendrite

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue TLA B 401

Chain	Residue
A	TYR42
B	LYS250
B	GLY253
B	ARG254
B	LEU255
B	HIS256

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site_id	AC2
Number of Residues	6
Details	binding site for residue FAR B 402

Chain	Residue
B	TRP52
B	PHE289
C	CMT195
B	TYR30
B	GLY49
B	ILE50

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site_id	AC3
Number of Residues	8
Details	binding site for residue GER B 403

Chain	Residue
B	GLN103
B	GLY192
B	GLN193
B	TYR195
B	CYS196
B	TYR241
B	TRP244
C	CYS194

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site_id	AC4
Number of Residues	8
Details	binding site for residue DPO B 404

Chain	Residue
A	LYS135
A	TYR191
A	SER193
B	HIS190
B	ARG232
B	LYS235
B	TYR241
C	CYS194

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
C	SER159
B	ASP238
B	CYS240
B	TYR241
B	HIS290

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Cysteine methyl ester => ECO:0000305

Chain	Residue	Details
C	CMT195

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site_id	SWS_FT_FI3
Number of Residues	1
Details	LIPID: S-palmitoyl cysteine => ECO:0000269|PubMed:15479160

Chain	Residue	Details
C	CYS194

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site_id	SWS_FT_FI4
Number of Residues	1
Details	LIPID: S-farnesyl cysteine => ECO:0000269|PubMed:15044687

Chain	Residue	Details
C	CMT195

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