6J5W
Ligand-triggered allosteric ADP release primes a plant NLR complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006952 | biological_process | defense response |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0043531 | molecular_function | ADP binding |
| A | 0050776 | biological_process | regulation of immune response |
| A | 0050829 | biological_process | defense response to Gram-negative bacterium |
| A | 0051707 | biological_process | response to other organism |
| A | 0098542 | biological_process | defense response to other organism |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006468 | biological_process | protein phosphorylation |
| B | 0006952 | biological_process | defense response |
| B | 0007166 | biological_process | cell surface receptor signaling pathway |
| B | 0009266 | biological_process | response to temperature stimulus |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 1900426 | biological_process | positive regulation of defense response to bacterium |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue ADP A 901 |
| Chain | Residue |
| A | VAL161 |
| A | LYS363 |
| A | HIS488 |
| A | LEU163 |
| A | GLY192 |
| A | GLY194 |
| A | LYS195 |
| A | THR196 |
| A | THR197 |
| A | LEU326 |
| A | PRO359 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 246 |
| Details | Domain: {"description":"NB-ARC","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 23 |
| Details | Repeat: {"description":"LRR 1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 24 |
| Details | Repeat: {"description":"LRR 2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 24 |
| Details | Repeat: {"description":"LRR 3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 23 |
| Details | Repeat: {"description":"LRR 4","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 23 |
| Details | Repeat: {"description":"LRR 5","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 26 |
| Details | Repeat: {"description":"LRR 6","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 51 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30948527","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6J5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6J6I","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30948526","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30948527","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6J5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6J5W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6J6I","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30948526","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6J5W","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
