6IUM
Crystal structure of enoyl-CoA hydratase (ECH) from Ralstonia eutropha H16
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003857 | molecular_function | 3-hydroxyacyl-CoA dehydrogenase activity |
| A | 0005777 | cellular_component | peroxisome |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006635 | biological_process | fatty acid beta-oxidation |
| A | 0009056 | biological_process | catabolic process |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0070403 | molecular_function | NAD+ binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003857 | molecular_function | 3-hydroxyacyl-CoA dehydrogenase activity |
| B | 0005777 | cellular_component | peroxisome |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006635 | biological_process | fatty acid beta-oxidation |
| B | 0009056 | biological_process | catabolic process |
| B | 0016042 | biological_process | lipid catabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0070403 | molecular_function | NAD+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 801 |
| Chain | Residue |
| A | TYR212 |
| A | HOH959 |
| B | LYS352 |
| B | GLN355 |
| B | ARG356 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 802 |
| Chain | Residue |
| B | GLY639 |
| B | MET437 |
| B | ALA512 |
| B | MET513 |
| B | TYR638 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 801 |
| Chain | Residue |
| A | ALA165 |
| A | GLY166 |
| A | THR167 |
| A | PHE170 |
| A | ASP171 |
| A | GLU172 |
| A | ILE173 |
| A | HOH1155 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 802 |
| Chain | Residue |
| A | LYS127 |
| A | PHE227 |
| A | PRO230 |
| A | HOH907 |
| A | HOH975 |
| A | HOH1096 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 803 |
| Chain | Residue |
| A | TYR657 |
| A | ALA660 |
| A | LEU661 |
| A | LYS664 |
| A | GLN682 |
| A | HOH942 |
| A | HOH1002 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 804 |
| Chain | Residue |
| A | ARG217 |
| A | LEU231 |
| A | GLU235 |
| A | GOL805 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 805 |
| Chain | Residue |
| A | PRO228 |
| A | LEU231 |
| A | LYS232 |
| A | GOL804 |
| A | HOH923 |
| A | HOH1046 |
| B | LYS291 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 806 |
| Chain | Residue |
| A | ARG252 |
| A | VAL259 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 807 |
| Chain | Residue |
| A | SER486 |
| A | PRO515 |
| A | MET518 |
| A | HOH903 |
| A | HOH1235 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 808 |
| Chain | Residue |
| A | ASN151 |
| A | TYR212 |
| A | ALA216 |
| A | HOH1243 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 809 |
| Chain | Residue |
| A | ASP652 |
| A | LEU656 |
| A | TYR657 |
| A | LYS689 |
| A | GLY690 |
| A | HOH1113 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 810 |
| Chain | Residue |
| A | ILE144 |
| A | ALA148 |
| A | LYS163 |
| A | PHE164 |
| A | HOH1179 |
