6IU6
Crystal structure of cytoplasmic metal binding domain with nickel ions
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005384 | molecular_function | manganese ion transmembrane transporter activity |
| A | 0030026 | biological_process | intracellular manganese ion homeostasis |
| B | 0005384 | molecular_function | manganese ion transmembrane transporter activity |
| B | 0030026 | biological_process | intracellular manganese ion homeostasis |
| C | 0005384 | molecular_function | manganese ion transmembrane transporter activity |
| C | 0030026 | biological_process | intracellular manganese ion homeostasis |
| D | 0005384 | molecular_function | manganese ion transmembrane transporter activity |
| D | 0030026 | biological_process | intracellular manganese ion homeostasis |
| E | 0005384 | molecular_function | manganese ion transmembrane transporter activity |
| E | 0030026 | biological_process | intracellular manganese ion homeostasis |
| F | 0005384 | molecular_function | manganese ion transmembrane transporter activity |
| F | 0030026 | biological_process | intracellular manganese ion homeostasis |
| H | 0005384 | molecular_function | manganese ion transmembrane transporter activity |
| H | 0030026 | biological_process | intracellular manganese ion homeostasis |
| I | 0005384 | molecular_function | manganese ion transmembrane transporter activity |
| I | 0030026 | biological_process | intracellular manganese ion homeostasis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 201 |
| Chain | Residue |
| A | GLU102 |
| A | GLU105 |
| A | NI202 |
| A | NI203 |
| A | HOH301 |
| D | HIS89 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue NI A 202 |
| Chain | Residue |
| A | MET149 |
| A | GLU153 |
| A | ZN201 |
| A | NI203 |
| A | HOH301 |
| A | GLU102 |
| A | GLU113 |
| A | GLU116 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue NI A 203 |
| Chain | Residue |
| A | GLU105 |
| A | GLU113 |
| A | GLU116 |
| A | ZN201 |
| A | NI202 |
| A | HOH301 |
| D | GLY87 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue NI A 204 |
| Chain | Residue |
| A | GLU127 |
| A | HIS129 |
| A | GLU130 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue ZN A 205 |
| Chain | Residue |
| A | GLY87 |
| A | HIS89 |
| A | NI206 |
| D | GLU102 |
| D | GLU105 |
| D | GLU113 |
| D | NI201 |
| D | HOH301 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue NI A 206 |
| Chain | Residue |
| A | GLY87 |
| A | ZN205 |
| D | GLU105 |
| D | GLU113 |
| D | GLU116 |
| D | GLU153 |
| D | NI201 |
| D | HOH301 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue ZN B 201 |
| Chain | Residue |
| B | GLU102 |
| B | GLU105 |
| B | GLU153 |
| B | ZN202 |
| B | NI203 |
| C | HIS89 |
| C | HOH301 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue ZN B 202 |
| Chain | Residue |
| B | GLU102 |
| B | GLU113 |
| B | GLU116 |
| B | GLU153 |
| B | ZN201 |
| B | NI203 |
| C | HOH301 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue NI B 203 |
| Chain | Residue |
| B | GLU105 |
| B | GLU113 |
| B | GLU116 |
| B | ZN201 |
| B | ZN202 |
| C | GLY87 |
| C | HOH301 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue ZN B 204 |
| Chain | Residue |
| B | HIS89 |
| B | GLU91 |
| C | GLU98 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue NI B 205 |
| Chain | Residue |
| B | HIS129 |
| B | GLU130 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue ZN B 206 |
| Chain | Residue |
| B | GLU98 |
| C | HIS89 |
| C | GLU91 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue ZN B 207 |
| Chain | Residue |
| B | GLY87 |
| B | HIS89 |
| B | NI208 |
| C | GLU102 |
| C | GLU105 |
| C | GLU153 |
| C | NI201 |
| C | HOH302 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue NI B 208 |
| Chain | Residue |
| B | GLY87 |
| B | ZN207 |
| C | GLU105 |
| C | GLU113 |
| C | GLU116 |
| C | GLU153 |
| C | NI201 |
| C | HOH302 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue NI C 201 |
| Chain | Residue |
| B | ZN207 |
| B | NI208 |
| C | GLU102 |
| C | GLU113 |
| C | GLU116 |
| C | MET149 |
| C | GLU153 |
| C | HOH302 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue NI C 202 |
| Chain | Residue |
| C | GLU127 |
| C | HIS129 |
| site_id | AD8 |
| Number of Residues | 9 |
| Details | binding site for residue NI D 201 |
| Chain | Residue |
| D | GLU113 |
| D | GLU116 |
| D | MET149 |
| D | GLU153 |
| D | HOH301 |
| A | ZN205 |
| A | NI206 |
| D | GLU102 |
| D | GLU105 |
| site_id | AD9 |
| Number of Residues | 2 |
| Details | binding site for residue NI D 202 |
| Chain | Residue |
| D | GLU127 |
| D | HIS129 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN E 201 |
| Chain | Residue |
| E | GLU102 |
| E | GLU105 |
| E | NI202 |
| E | NI203 |
| H | HIS89 |
| H | HOH302 |
| site_id | AE2 |
| Number of Residues | 8 |
| Details | binding site for residue NI E 202 |
| Chain | Residue |
| E | GLU102 |
| E | GLU113 |
| E | GLU116 |
| E | MET149 |
| E | GLU153 |
| E | ZN201 |
| E | NI203 |
| H | HOH302 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue NI E 203 |
| Chain | Residue |
| E | GLU105 |
| E | GLU113 |
| E | GLU116 |
| E | ZN201 |
| E | NI202 |
| H | GLY87 |
| H | HOH302 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue NI E 204 |
| Chain | Residue |
| E | GLU127 |
| E | HIS129 |
| E | GLU130 |
| site_id | AE5 |
| Number of Residues | 8 |
| Details | binding site for residue ZN E 205 |
| Chain | Residue |
| E | GLY87 |
| E | HIS89 |
| E | NI206 |
| H | GLU102 |
| H | GLU105 |
| H | GLU113 |
| H | NI201 |
| H | HOH301 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue NI E 206 |
| Chain | Residue |
| E | GLY87 |
| E | ZN205 |
| H | GLU105 |
| H | GLU113 |
| H | GLU116 |
| H | NI201 |
| H | HOH301 |
| site_id | AE7 |
| Number of Residues | 9 |
| Details | binding site for residue ZN F 201 |
| Chain | Residue |
| F | GLU102 |
| F | GLU105 |
| F | GLU113 |
| F | GLU153 |
| F | NI202 |
| F | NI203 |
| F | HOH302 |
| I | GLY87 |
| I | HIS89 |
| site_id | AE8 |
| Number of Residues | 8 |
| Details | binding site for residue NI F 202 |
| Chain | Residue |
| F | GLU102 |
| F | GLU113 |
| F | GLU116 |
| F | MET149 |
| F | GLU153 |
| F | ZN201 |
| F | NI203 |
| F | HOH302 |
| site_id | AE9 |
| Number of Residues | 8 |
| Details | binding site for residue NI F 203 |
| Chain | Residue |
| F | GLU105 |
| F | GLU113 |
| F | GLU116 |
| F | GLU153 |
| F | ZN201 |
| F | NI202 |
| F | HOH302 |
| I | GLY87 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue NI F 204 |
| Chain | Residue |
| F | GLU127 |
| F | HIS129 |
| F | GLU130 |
| site_id | AF2 |
| Number of Residues | 7 |
| Details | binding site for residue ZN F 205 |
| Chain | Residue |
| F | GLY87 |
| F | HIS89 |
| F | NI206 |
| F | HOH301 |
| I | GLU102 |
| I | GLU105 |
| I | NI201 |
| site_id | AF3 |
| Number of Residues | 7 |
| Details | binding site for residue NI F 206 |
| Chain | Residue |
| F | GLY87 |
| F | ZN205 |
| F | HOH301 |
| I | GLU105 |
| I | GLU113 |
| I | GLU116 |
| I | NI201 |
| site_id | AF4 |
| Number of Residues | 8 |
| Details | binding site for residue NI H 201 |
| Chain | Residue |
| E | ZN205 |
| E | NI206 |
| H | GLU102 |
| H | GLU113 |
| H | GLU116 |
| H | MET149 |
| H | GLU153 |
| H | HOH301 |
| site_id | AF5 |
| Number of Residues | 2 |
| Details | binding site for residue NI H 202 |
| Chain | Residue |
| H | GLU127 |
| H | HIS129 |
| site_id | AF6 |
| Number of Residues | 8 |
| Details | binding site for residue NI I 201 |
| Chain | Residue |
| F | ZN205 |
| F | NI206 |
| F | HOH301 |
| I | GLU102 |
| I | GLU113 |
| I | GLU116 |
| I | MET149 |
| I | GLU153 |
| site_id | AF7 |
| Number of Residues | 3 |
| Details | binding site for residue ZN I 202 |
| Chain | Residue |
| B | GLU127 |
| I | GLU127 |
| I | HIS129 |
