Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0006108 | biological_process | malate metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016615 | molecular_function | malate dehydrogenase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0030060 | molecular_function | L-malate dehydrogenase (NAD+) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | binding site for residue NAD A 401 |
| Chain | Residue |
| A | GLY7 |
| A | GLY78 |
| A | VAL79 |
| A | ALA80 |
| A | ASN94 |
| A | ILE117 |
| A | THR118 |
| A | ASN119 |
| A | VAL121 |
| A | ILE146 |
| A | HIS177 |
| A | ALA9 |
| A | ALA224 |
| A | THR225 |
| A | MET228 |
| A | HOH502 |
| A | HOH514 |
| A | HOH531 |
| A | HOH536 |
| A | HOH542 |
| A | HOH543 |
| A | HOH557 |
| A | GLY10 |
| A | HOH578 |
| A | HOH602 |
| A | GLY11 |
| A | ILE12 |
| A | TYR33 |
| A | ASP34 |
| A | SER76 |
| A | ALA77 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | ASP71 |
| A | LEU239 |
| A | SER243 |
| A | GLY271 |
| A | THR272 |
| A | GLU273 |
| A | GLY274 |
| A | HOH501 |
Functional Information from PROSITE/UniProt
| site_id | PS00068 |
| Number of Residues | 13 |
| Details | MDH Malate dehydrogenase active site signature. ITTLDilRAetfI |
| Chain | Residue | Details |
| A | ILE146-ILE158 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_01516","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 15 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01516","evidenceCode":"ECO:0000255"}]} |
