6ISQ
structure of Lipase mutant with oxided Cys-His-Asp catalytic triad
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004806 | molecular_function | triacylglycerol lipase activity |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004806 | molecular_function | triacylglycerol lipase activity |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0016042 | biological_process | lipid catabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 401 |
| Chain | Residue |
| A | THR40 |
| A | CSD105 |
| A | GLN157 |
| A | ILE189 |
| A | IPA402 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue IPA A 402 |
| Chain | Residue |
| A | PRO280 |
| A | ACT401 |
| A | GLY39 |
| A | THR40 |
| A | CSD105 |
| A | HIS224 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | LYS136 |
| A | ARG168 |
| A | HOH504 |
| A | HOH511 |
| A | HOH621 |
| B | ASP296 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | MET-1 |
| A | THR174 |
| A | GLN175 |
| A | ASN206 |
| A | HOH560 |
| B | ALA92 |
| B | GLY95 |
| B | ASN96 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | ASP252 |
| A | THR256 |
| A | ASP257 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue PGE A 407 |
| Chain | Residue |
| A | GLU188 |
| A | ASP223 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 401 |
| Chain | Residue |
| B | THR40 |
| B | CSD105 |
| B | GLN157 |
| B | ILE189 |
| B | IPA402 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue IPA B 402 |
| Chain | Residue |
| B | GLY39 |
| B | THR40 |
| B | VAL104 |
| B | CSD105 |
| B | HIS224 |
| B | PRO280 |
| B | ACT401 |
| B | HOH561 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"8527460","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"8087556","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8527460","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
