6ISP

structure of Candida antarctica Lipase B mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004806	molecular_function	triacylglycerol lipase activity
A	0006629	biological_process	lipid metabolic process
A	0016042	biological_process	lipid catabolic process
A	0016787	molecular_function	hydrolase activity
B	0004806	molecular_function	triacylglycerol lipase activity
B	0006629	biological_process	lipid metabolic process
B	0016042	biological_process	lipid catabolic process
B	0016787	molecular_function	hydrolase activity
C	0004806	molecular_function	triacylglycerol lipase activity
C	0006629	biological_process	lipid metabolic process
C	0016042	biological_process	lipid catabolic process
C	0016787	molecular_function	hydrolase activity
D	0004806	molecular_function	triacylglycerol lipase activity
D	0006629	biological_process	lipid metabolic process
D	0016042	biological_process	lipid catabolic process
D	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue CPQ D 401

Chain	Residue
A	CPQ403
D	THR186
D	ASN196
D	PRO218
D	PHE220
D	CPQ402
D	HOH501
D	HOH535
D	HOH597

---

site_id	AC2
Number of Residues	3
Details	binding site for residue CPQ D 402

Chain	Residue
A	PRO218
D	ALA287
D	CPQ401

---

site_id	AC3
Number of Residues	7
Details	binding site for residue CA A 401

Chain	Residue
A	ASP223
A	HOH668
A	HOH699
D	ASP223
D	HOH651
D	HOH691
D	HOH698

---

site_id	AC4
Number of Residues	18
Details	binding site for residue CPQ A 402

Chain	Residue
A	THR186
A	VAL194
A	SER195
A	ASN196
A	SER197
A	LEU199
A	GLN213
A	PRO218
A	PHE220
A	CPQ404
A	CPQ405
A	HOH519
A	HOH579
A	HOH665
A	HOH671
C	ARG302
C	THR316
C	PRO317

---

site_id	AC5
Number of Residues	9
Details	binding site for residue CPQ A 403

Chain	Residue
A	PRO143
A	TYR282
A	HOH531
A	HOH602
A	HOH638
D	LEU140
D	ALA185
D	GLN191
D	CPQ401

---

site_id	AC6
Number of Residues	8
Details	binding site for residue CPQ A 404

Chain	Residue
A	VAL139
A	LEU140
A	ALA185
A	THR186
A	GLN191
A	CPQ402
A	HOH561
D	LEU144

---

site_id	AC7
Number of Residues	7
Details	binding site for residue CPQ A 405

Chain	Residue
A	GLN46
A	PHE71
A	ALA283
A	ALA284
A	ALA287
A	CPQ402
C	PRO317

---

site_id	AC8
Number of Residues	4
Details	binding site for residue CPQ C 401

Chain	Residue
B	CPQ402
C	CPQ402
C	CPQ403
C	HOH633

---

site_id	AC9
Number of Residues	11
Details	binding site for residue CPQ C 402

Chain	Residue
B	CPQ402
C	THR186
C	VAL194
C	GLN213
C	PRO218
C	PHE220
C	CPQ401
C	HOH517
C	HOH622
C	HOH633
C	HOH816

---

site_id	AD1
Number of Residues	9
Details	binding site for residue CPQ C 403

Chain	Residue
C	GLN46
C	PHE71
C	ALA283
C	ALA287
C	CPQ401
C	HOH506
C	HOH514
C	HOH633
C	HOH801

---

site_id	AD2
Number of Residues	7
Details	binding site for residue CA B 401

Chain	Residue
B	ASP223
B	HOH674
B	HOH704
B	HOH706
C	ASP223
C	HOH646
C	HOH673

---

site_id	AD3
Number of Residues	9
Details	binding site for residue CPQ B 402

Chain	Residue
C	CPQ401
C	CPQ402
B	THR186
B	VAL194
B	GLN213
B	PRO218
B	PHE220
B	HOH562
B	HOH651

---

site_id	AD4
Number of Residues	4
Details	binding site for residue CPQ B 403

Chain	Residue
B	ALA185
B	THR186
B	HOH559
C	PRO143

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"evidences":[{"source":"PubMed","id":"8527460","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"8087556","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8527460","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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