6IP9

Crystal Structure of Lanthanum ion (La3+) bound bovine alpha-lactalbumin

Replaces:  5X84

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003796	molecular_function	lysozyme activity
A	0004461	molecular_function	lactose synthase activity
A	0005509	molecular_function	calcium ion binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005989	biological_process	lactose biosynthetic process
A	0032355	biological_process	response to estradiol
A	0032570	biological_process	response to progesterone
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	1903494	biological_process	response to dehydroepiandrosterone
A	1903496	biological_process	response to 11-deoxycorticosterone

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue SO4 A 201

Chain	Residue
A	LYS16
A	SER22
A	LEU23
A	PRO24
A	ASN56
A	TRP60
A	VAL99
A	TYR103

---

site_id	AC2
Number of Residues	4
Details	binding site for residue GOL A 202

Chain	Residue
A	ARG10
A	ARG10
A	ASN45
A	CYS6

---

site_id	AC3
Number of Residues	8
Details	binding site for residue LA A 203

Chain	Residue
A	LYS79
A	ASP82
A	ASP84
A	ASP87
A	ASP88
A	HOH310
A	HOH322
A	HOH326

---

Functional Information from PROSITE/UniProt

site_id	PS00128
Number of Residues	19
Details	GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnisCdkFlddDLtddimC

Chain	Residue	Details
A	CYS73-CYS91

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:8805552, ECO:0007744|PDB:1HFZ

Chain	Residue	Details
A	LYS79
A	ASP82
A	ASP84
A	ASP87
A	ASP88

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN45

---